Tardive dyskinesia on low dose risperidone

Area of Science:

• Neurology
• Psychiatry
• Pharmacology

Background:

• Tardive dyskinesia (TD) is a neurological disorder characterized by involuntary, purposeless movements, often in the oro-facial region.
• Risk factors for TD are inconsistently reported but may include female sex, substance misuse, affective disorders, intellectual disability, and antipsychotic medication details.
• Antipsychotic medication dose, class, and duration are potential independent risk factors for developing TD.

Purpose of the Study:

• To report a case of tardive dyskinesia (TD) developing in a patient treated with a low dose of a second-generation antipsychotic.
• To contribute to the understanding of risk factors for TD, particularly concerning newer antipsychotic medications.

Main Methods:

• Case report detailing the clinical presentation and treatment of a patient who developed tardive dyskinesia.
• Review of relevant literature on tardive dyskinesia risk factors and antipsychotic medication associations.

Main Results:

• The patient developed tardive dyskinesia despite receiving a low dose of risperidone, a second-generation antipsychotic.
• This case suggests that TD can occur even with seemingly low-risk medication profiles.

Conclusions:

• Tardive dyskinesia may develop even with low doses of second-generation antipsychotics like risperidone.
• Clinicians should remain vigilant for TD symptoms in patients treated with antipsychotics, regardless of dose.
• Further research is needed to fully elucidate the risk factors for TD in the context of modern antipsychotic treatments.