Related Experiment Video
Updated: Feb 4, 2026

Using an Automated Hirschberg Test App to Evaluate Ocular Alignment
Published on: March 24, 2020
Evaluation of ocular motility deviation changes in exotropic patients after cycloplegic eye drops versus prism
Alon Zahavi1,2, Ronit Friling2,3, Yonina Ron2,3
1Department of Ophthalmology, Rabin Medical Center-Beilinson Hospital, Petach Tikva, Israel.
Purpose:
To evaluate changes in ocular motility deviation with cycloplegic eye drop examination compared to the prism adaptation test in patients with strabismus.
Methods:
The medical charts were reviewed of all patients who underwent primary strabismus surgery in our center from December 2013 to July 2015. Data collected included demographics, medical history, and findings on pre-operative ophthalmic/orthoptic examination. Ocular motility deviation was measured before instillation of cycloplegic eye drops, immediately after maximal dilation (end point), and 10 and 20 min later. Prism adaptation test readings were taken at baseline, immediately after prism removal (end point), and 10 and 20 min later.
Results:
A total of 43 patients had complete pre- and post-operative evaluations. Our analysis focused only on the exotropic patients (n = 33). On cycloplegics, there was no significant difference in ocular motility deviation between baseline and end point for distance and near (p = 0.584, p = 0.468, respectively). On prism adaptation test, comparison of ocular motility deviation between baseline and end point was statistically significant for distance and near (p = 0.002, p = 0.001, respectively). Changes remained significant 10 min after the end point for near (p = 0.011). Comparison at the end points between the tests revealed statistical significance for distance and near, favoring the prism adaptation test (p = 0.001 and p < 0.001, respectively). This significance was maintained even after 10 min for near (p = 0.036).
Conclusion:
The prism adaptation test is preferred over cycloplegic eye drops for the evaluation of maximal reserve of distance/near motility before surgical correction of exotropia.
Related Concept Videos
Variation: Normal Distribution, Range, and Standard Deviation
Standard Deviation
Mean Absolute Deviation
Let us consider a dataset containing the number of unsold cupcakes in five shops: 10, 15, 8, 7, and 10. Initially, calculate the sample mean. Then calculate the deviation, or the difference, between each data value and the mean. Next, the absolute values of these deviations are added and divided by the sample size to...
Standard Deviation of Calculated Results
A broad Gaussian distribution curve has a wider standard deviation, representing a data set with...
Calculating Standard Deviation
The standard deviation value is small when all the data is concentrated close to the mean. Here the data exhibits low variation. The standard deviation value is larger when the data values are more spread out from the mean. Here, the data displays high...
Estimating Population Mean with Known Standard Deviation
The confidence interval estimate will have the form as follows:
(point estimate - error bound, point estimate +...

