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Updated: Feb 4, 2026

Development of a Direct Pulp-capping Model for the Evaluation of Pulpal Wound Healing and Reparative Dentin Formation in Mice
Published on: January 12, 2017
Study to evaluate the Efficacy of Resin-modified Glass lonomer Cement Liner as a Direct Pulp Capping Material
Abdul Shameem1, Sabir Muliyar2, Rekha P Thankachan2
1Department of Conservative Dentistry and Endodontics MES Dental College and Hospital, Malappuram, Kerala, India,
Aim:
The aim of the present in vivo study was to compare efficacy of light-cured resin-modified glass ionomer liner, Vitrebond™ (3M ESPE) with Dycal® (Dentsply) on the healing of pulpal tissue in the event of a direct iatrogenic pulpal exposure.
Materials And Methods:
Experimental group consisted of Vitrebond™ (3M ESPE) resin-modified glass ionomer liner, and Vitremer™ (3M ESPE) resin-modified glass ionomer cement (GIC) in comparison with the control group of Dycal® (Dentsply) as liner and Poly F® (Dentsply) dental cement. Class V cavities were prepared in 32 sound premolars that were scheduled for orthodontic extraction, and the exposures were capped according to groups. Five teeth from each group were extracted under local anesthesia after an interval of 24 hours, 35 and 60 days, and evaluated for inflammation, fibrotic changes, formation of reparative dentin and bacterial examination.
Results:
The present study did not show any statistically significant difference between two groups in terms of inflammation, fibrosis, reparative dentin formation, and bacterial examination.
Conclusion:
This study shows that Vitrebond™ (3M ESPE) light-cured resin-modified glass ionomer liner can be used as an alternative to calcium hydroxide as a direct pulp capping material.
Clinical Significance:
Light-cured resin-modified glass ionomer liner can be an alternative for the calcium hydroxide-based liner for capping iatrogenic pulp exposures.
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