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Related Concept Videos

Overview of the Cardiovascular System01:14

Overview of the Cardiovascular System

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The cardiovascular system is a vital transportation system in the body. It comprises the heart and blood vessels and facilitates the exchange of gases, nutrients, and waste products.
Heart
The heart is the central pump of the cardiovascular system that circulates blood throughout the body. It comprises two atria receiving the blood and two ventricles pumping blood out of the heart. Their rhythmic contractions, called heartbeats, ensure that blood flow remains continuous.
Blood Vessels
Blood...
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Regulation of the Cardiovascular System01:27

Regulation of the Cardiovascular System

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The regulation of the cardiovascular system allows the body to adapt to various demands and maintain homeostasis.
The regulation of the cardiovascular system involves the autonomic nervous system (ANS), baroreceptors, and chemoreceptors, ensuring that heart rate and blood pressure are appropriately modulated in response to varying physiological demands.
The ANS comprises two main divisions: the sympathetic and parasympathetic nervous systems. The sympathetic nervous system enhances...
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Exercise and Cardiovascular Response01:20

Exercise and Cardiovascular Response

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Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
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Assessment of the Cardiovascular System II: Inspection01:29

Assessment of the Cardiovascular System II: Inspection

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Inspection is the initial step in assessing the cardiovascular system. It involves a detailed visual examination that provides crucial information about a patient's circulatory and cardiac health. This systematic process, conducted from head to toe, helps identify signs of cardiovascular conditions by observing physical appearance, skin and mucous membranes, jugular and carotid pulsations, chest symmetry, and the condition of the extremities.
Head and Neck
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Psychoneuroimmunology: Cardiovascular Disease01:27

Psychoneuroimmunology: Cardiovascular Disease

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Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
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Assessment of the Cardiovascular System IV: Auscultation01:25

Assessment of the Cardiovascular System IV: Auscultation

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Cardiac auscultation is a clinical skill used to assess heart function and detect abnormalities. It involves listening to heart sounds at specific anatomical locations through a stethoscope.
Normal Heart Sounds
S1 (First Heart Sound)-
S1 is made by the closure of the mitral and tricuspid valves (atrioventricular valves), marking the beginning of systole.
S2 (Second Heart Sound)-
S2 is made by the closure of the aortic and pulmonic valves (semilunar valves), marking the end of the systole.
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In Silico Clinical Trials for Cardiovascular Disease
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Hypothyroidism and cardiovascular system.

A F Verbovoy, A Sharonova Lyudmila, O V Kosareva

    Klinicheskaia Meditsina
    |October 6, 2018
    PubMed
    Summary

    Hypothyroidism is linked to cardiovascular disease through factors like dyslipidemia and vitamin D deficiency. Understanding these connections aids in managing heart health in hypothyroid patients.

    Area of Science:

    • Endocrinology
    • Cardiology
    • Metabolic Syndrome

    Background:

    • Thyroid dysfunction, particularly hypothyroidism, is increasingly recognized for its association with cardiovascular complications.
    • Cardiovascular diseases (CVD) remain a leading cause of morbidity and mortality worldwide.
    • Understanding the specific mechanisms linking hypothyroidism to CVD is crucial for effective patient management.

    Purpose of the Study:

    • To investigate the relationship between thyroid dysfunction and cardiovascular diseases.
    • To elucidate the role of specific biomarkers and risk factors in the development of CVD in hypothyroid individuals.
    • To analyze myocardial remodeling and dysfunction in the context of hypothyroidism and associated cardiovascular risk factors.

    Main Methods:

    • Data analysis of patients with thyroid dysfunction and cardiovascular diseases.

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  • Review of literature concerning dyslipidemia, adipokines, C-reactive protein, and vitamin D3 deficiency in hypothyroidism-related CVD.
  • Examination of myocardial remodeling and dysfunction characteristics and their correlation with cardiovascular risk factors.

    • Main Results:

    • Hypothyroidism is associated with dyslipidemia, altered adipokine levels (adiponectin, leptin, resistin), elevated C-reactive protein, and vitamin D3 deficiency.
    • These factors contribute to the development and progression of cardiovascular disease in patients with hypothyroidism.
    • Specific characteristics of myocardial remodeling and dysfunction were identified and correlated with established cardiovascular risk factors.

    Conclusions:

    • Thyroid dysfunction significantly impacts cardiovascular health, mediated by metabolic and inflammatory pathways.
    • Dyslipidemia, adipokine imbalance, inflammation, and vitamin D3 deficiency are key contributors to CVD in hypothyroidism.
    • Targeting these factors may offer therapeutic strategies for reducing cardiovascular risk in patients with hypothyroidism.