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Published on: September 12, 2020
Management of patients with stroke treated with direct oral anticoagulants
D J Seiffge1,2, A A Polymeris1, J Fladt1
1Neurology and Stroke Center, Department of Clinical Research, University Hospital and University of Basel, Petersgraben 4, 4031, Basel, Switzerland.
Insights
Direct oral anticoagulants (DOACs) are common for preventing strokes in atrial fibrillation patients. Managing these patients after a stroke presents clinical challenges, driving new research in this area.
Area of Science:
- Cardiology
- Neurology
- Pharmacology
Background:
- Direct oral anticoagulants (DOACs) are increasingly prescribed for stroke prevention in atrial fibrillation.
- Physicians face challenges managing DOAC-treated patients experiencing stroke.
Purpose of the Study:
- To review current research on managing stroke in patients treated with direct oral anticoagulants.
- To address clinical challenges in acute and long-term care settings.
Main Methods:
- Literature review of recent studies on DOACs and stroke management.
- Synthesis of research findings on challenges and solutions.
Main Results:
- DOAC use for stroke prevention is rising globally.
- Specific management strategies for DOAC-related stroke are under active investigation.
- Clinical practice guidelines are evolving to address these complexities.
Conclusions:
- Effective management of DOAC-treated stroke patients requires ongoing research and updated clinical protocols.
- Addressing these challenges is crucial for optimizing patient outcomes.
Abstract:
Since their market approval, direct oral anticoagulants (DOACs) are being increasingly used for stroke prevention in patients with atrial fibrillation. However, the management of DOAC-treated patients with stroke poses several challenges for physicians in everyday clinical practice, both in the acute setting and in long-term care. This has spurred extensive research activity in the field over the past few years, which we review here.
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