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Published on: September 20, 2018
Childhood Pemphigus Vulgaris: Report of Two Cases with Emphasis on Diagnostic Approach
Varun Surya1, Priya Kumar1, Sunita Gupta2
1Department of Oral Pathology, Maulana Azad Institute of Dental Sciences, New Delhi, India.
Insights
Childhood pemphigus vulgaris (CPV) is rare but mimics other oral conditions. Early diagnosis is crucial for effective management and minimizing complications in children.
Area of Science:
- Dermatology
- Pediatrics
- Autoimmune Blistering Diseases
Background:
- Childhood pemphigus vulgaris (CPV) presents challenges in diagnosis due to its rarity and resemblance to more common pediatric oral conditions.
- Effective management of CPV requires early and accurate diagnosis to prevent significant morbidity.
Observation:
- Two cases of childhood pemphigus vulgaris are presented, highlighting the diagnostic process.
- Clinical presentation of CPV can be mistaken for herpetic gingivostomatitis, a prevalent condition in children.
Findings:
- The study emphasizes the diagnostic approach for childhood pemphigus vulgaris.
- Timely diagnosis is critical for appropriate treatment and minimizing adverse effects.
Implications:
- This case series underscores the importance of considering CPV in the differential diagnosis of pediatric oral lesions.
- Prompt diagnosis and tailored treatment strategies are essential for improving outcomes in children with CPV.
Abstract:
Childhood pemphigus vulgaris (CPV) is a rare entity with clinical features and management primarily similar to those of adults; diagnosis may be difficult due to clinical similarity to other disorders such as herpetic gingivostomatitis which is more prevalent in this age group. We report two cases of CPV with emphasis on diagnostic approach. While treating such patients, it is imperative to diagnose CPV in the early stages to prevent serious morbidity and to adjust drug dosage to minimize side effects.
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