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Surfaces with Dual Functionality through Specific Coimmobilization of Self-Assembled Polymeric Nanostructures
Serena Rigo1, Gesine Gunkel-Grabole1, Wolfgang Meier1
1Department of Chemistry , University of Basel , Mattenstrasse 24a, BPR 1096 , CH-4002 Basel , Switzerland.
Langmuir : the ACS Journal of Surfaces and Colloids
|October 9, 2018
Summary
Researchers developed a novel method to coimmobilize nanoassemblies onto surfaces using click chemistry. This technique enables the creation of advanced, dually functionalized active surfaces for diverse applications like catalysis and biosensing.
Area of Science:
- Surface chemistry and nanotechnology
- Materials science and engineering
Background:
- Nanoassemblies like micelles, polymersomes, and nanoparticles are crucial for developing active surfaces.
- Applications include catalysis, biosensing, and antimicrobial surfaces, demanding versatile immobilization strategies.
Purpose of the Study:
- To present a novel method for simultaneously coimmobilizing various nanoassemblies onto solid supports.
- To detail the immobilization process using bio-orthogonal and catalyst-free click reactions.
- To explore the creation of patterned surfaces using microstamping techniques.
Main Methods:
- Utilized a combination of strain-promoted azide-alkyne click (SPAAC) and thiol-ene reactions for coimmobilization.
- Investigated the SPAAC reaction for attaching soft, polymeric assemblies (polymersomes, micelles) to surfaces.
- Employed poly(dimethylsiloxane) (PDMS)-based polymersomes as 'ink' for microstamped pattern generation.
Main Results:
- Successfully coimmobilized polymersome-polymersome and polymersome-micelle assemblies onto surfaces.
- Demonstrated the effectiveness of SPAAC and thiol-ene reactions for simultaneous immobilization of diverse nanoassemblies.
- Achieved locally defined surface patterns using microstamping with PDMS-based polymersomes.
Conclusions:
- The combined SPAAC and thiol-ene reactions offer a versatile platform for creating dually functionalized active surfaces.
- This approach allows for the precise engineering of interfacial properties by coimmobilizing various nanoassembly pairs.
- The developed method paves the way for multifunctional surfaces with enhanced properties and efficiency for advanced applications.
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