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Updated: Feb 4, 2026

A Zebrafish Model of Diabetes Mellitus and Metabolic Memory
Published on: February 28, 2013
[ADHERENCE TO THE TREATMENT IN PATIENTS WITH TYPE 2 DIABETES MELLITUS AND WAYS TO ITS OPTIMIZATION]
Abstract:
A total of 148 patients (50 men and 98 women) with type 2 diabetes who were hospitalized in the endocrinology department «Nizhny Novgorod Regional Hospital N.A. Semashko». It was shown based on the Morisky-Green scale that 91 patients (61.4%) did not comply with the doctor's recommendation. 57 (38.6%) patients adhered to the treatment. The patients showing poor compliance with the treatment were divided randomly into two groups. One was comprised of patients with type 2 diabetes (n = 45) who had been trained in the school of diabetic patients, provided with a special literature and kept a diary of self-monitoring blood glucose. The second group consisted of patients with type 2 diabetes (n = 46) also trained at the school of diabetes and provided with the relevant literature but were under active control (telephone calls, visits to the center). The year-long prospective study demonstrated that adherence to treatment increased in the entire cohort. However, statistically significant positive dynamics of clinical and biochemical parameters was achieved only in the group of patients actively monitored by medical personnel.
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