Related Experiment Video
Updated: Feb 4, 2026

Murine Model of Wound Healing
Published on: May 28, 2013
Effects of Occlusion on Periodontal Wound Healing
1Professor and Director of Graduate Periodontics, Department of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, Michigan.
Abstract:
Trauma from occlusion remains an important concept in dentistry. Traumatic occlusion affects the biological system through a series of events that induces an aseptic inflammatory response and bone resorption. Clinical evidence of these biological events is present in the form of active traumatic lesions or adaptive mechanisms. If these clinical signs are not identified prior to periodontal surgery, failure of the procedure could result due to an exacerbated leukocyte presence and unresolving wound. However, if traumatic occlusion is adjusted, evidence demonstrates that even large inflammatory events such as replantation of an avulsed tooth can be successful. Thus, harmony of occlusal contacts without interference is essential in achieving predictable periodontal/implant bone regeneration.
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