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Treading the beaten path with old and new obstacles: a report from the Indian HIPEC registry
Aditi Bhatt1, Sanket S Mehta2, Shabber Zaveri3
1a Department of Surgical Oncology , Fortis Hospital , Bangalore , India.
Insights
The Indian HIPEC registry evaluated surgical outcomes for peritoneal metastases, finding it a valuable research tool despite operational challenges like data entry issues. This collaboration demonstrates feasibility without external funding.
Area of Science:
- Surgical Oncology
- Clinical Research
- Health Informatics
Background:
- The Indian HIPEC registry was established by surgeons to track patients with peritoneal metastases undergoing cytoreductive surgery +/- HIPEC.
- The registry aimed to evaluate treatment outcomes and identify operational challenges within the Indian healthcare system.
Purpose of the Study:
- To assess the outcomes of cytoreductive surgery with or without HIPEC for peritoneal metastases using registry data.
- To identify and address operational problems hindering the registry's efficiency and data quality.
Main Methods:
- A retrospective analysis of 332 patients from March 2016 to September 2017 across 8 centers.
- An online survey was conducted to understand surgeon practices and identify registry-related operational issues.
Main Results:
- High rates of complete tumor resection (CC-0/1: 94.7%) were achieved, with no significant differences in morbidity or mortality between centers.
- A high failure-to-rescue rate (19.3%) and inferior survival for colorectal peritoneal metastases were observed.
- Key operational problems included a lack of dedicated data personnel and incomplete electronic medical record systems.
Conclusions:
- The registry validates current practices and highlights specific challenges within India that require attention.
- Despite operational hurdles, the registry serves as a crucial tool for audit and research.
- The project demonstrates successful surgeon collaboration without regulatory oversight or dedicated funding.
Background:
The Indian HIPEC registry is a self-funded registry instituted by a group of Indian surgeons for patients with peritoneal metastases (PM) undergoing surgical treatment. This work was performed to • Evaluate outcomes of cytoreductive surgery ± HIPEC in patients enrolled in the registry. • Identify operational problems.
Methods:
A retrospective analysis of patients enrolled in the registry from March 2016 to September 2017 was performed. An online survey was performed to study the surgeons' attitudes and existing practices pertaining to the registry and identify operational problems.
Results:
During the study period, 332 patients were enrolled in 8 participating centres. The common indication was ovarian cancer for three centres and pseudomyxoma peritonei for three others. The median PCI ranged from 3 to 23. A CC-0/1 resection was obtained in 94.7%. There was no significant difference in the morbidity (p = .25) and mortality (p = .19) rates between different centres. There was a high rate of failure-to-rescue (19.3%) patients with complications and the survival in patients with colorectal PM was inferior. A lack of dedicated personnel for data collection and entry was the main reason for only 10/43 surgeons contributing data. The other problem was the lack of complete electronic medical record systems at all centres.
Conclusions:
These results validate existing practices and identify country-specific problems that need to be addressed. Despite operational problems, the registry is an invaluable tool for audit and research. It shows the feasibility of fruitful collaboration between surgeons in the absence of any regulatory body or funding for the project.
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