Related Experiment Video
Updated: Aug 7, 2026
10:28
Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT
Published on: January 22, 2018
The INDEPSO-ISPSM Consensus on Peritoneal Malignancies-Gastric Cancer Peritoneal Metastases
Aruna Prabhu1, Vivek Sukumar2, Aditi Bhatt3
1Department of Surgical Oncology, Thangam Cancer Center, 54, Dr. Sankaran Road, Trichy Main Road, Namakkal, Tamil Nadu 637001 India.
Indian Journal of Surgical Oncology
|August 6, 2026
Summary
Gastric peritoneal metastases (PM) management recommendations were established using a consensus exercise. Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) are recommended for selected patients with gastric PM.
Area of Science:
- Gastroenterology
- Surgical Oncology
- Clinical Research
Background:
- Gastric peritoneal metastases (PM) present limited evidence for management strategies.
- A consensus exercise was conducted to address these management challenges.
Purpose of the Study:
- To provide evidence-based recommendations for managing gastric PM.
- To establish consensus on key aspects of gastric PM treatment.
Main Methods:
- Modified Delphi technique employed for consensus building.
- Twenty-four questions across 8 topics were addressed by 43 experts.
- Consensus defined as >70% agreement on an option.
Main Results:
- Consensus achieved on 20/24 (83.3%) questions.
- Cytoreductive surgery (CRS) recommended for selected patients (PCI ≤ 6) in specialized centers.
- Hyperthermic intraperitoneal chemotherapy (HIPEC) recommended post-CRS for CC-0 resections, including select signet ring cell cancers.
- Prophylactic HIPEC recommended only within clinical trials.
- Systemic chemotherapy alone recommended for newly-diagnosed PM; PIPAC showed lower consensus.
Conclusions:
- CRS and HIPEC are recommended for well-selected gastric PM patients, including signet ring cell types.
- Intraperitoneal treatments for prophylaxis and newly-diagnosed PM are not recommended outside clinical trials.
- These recommendations offer guidance for clinicians managing gastric PM.
