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Determining Glucose Metabolism Kinetics Using 18F-FDG Micro-PET/CT
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FDG PET/CT in a Case of Dural Amyloidoma

Pengcheng Ran1, Yupin Liu2, Xiang Liang1

  • 1From the Departments of Nuclear Medicine.

Clinical Nuclear Medicine
|October 10, 2018
PubMed

Insights

Dural amyloidoma, a rare form of central nervous system amyloidosis, can present as dural thickening. This condition may show abnormal fluorodeoxyglucose (FDG) uptake on PET/CT scans, aiding diagnosis.

Area of Science:

  • Neurology
  • Radiology
  • Pathology

Background:

  • Dural amyloidoma is an uncommon manifestation of central nervous system amyloidosis.
  • Amyloid deposition in the dura mater is rare and can mimic other dural pathologies.

Observation:

  • A 49-year-old female presented with recurrent vertigo.
  • MRI revealed dural thickening with characteristic signal intensity and postcontrast enhancement.
  • Surgical biopsy confirmed the diagnosis of dural amyloidoma.

Findings:

  • The resected lesion showed residual dural amyloidoma.
  • Follow-up FDG PET/CT demonstrated increased metabolic activity in the remaining lesion.
  • This highlights FDG uptake as a potential imaging biomarker.

Implications:

  • Dural amyloidoma should be considered in the differential diagnosis of enhancing dural lesions.
  • FDG PET/CT can aid in identifying and monitoring dural amyloidoma.
  • Further research into the pathophysiology and diagnostic criteria for dural amyloidoma is warranted.

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