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Image Acquisition Method for the Sonographic Assessment of the Inferior Vena Cava
Published on: January 13, 2023
Inferior vena cava assessment can predict contrast-induced nephropathy in patients undergoing cardiac
Fatih Gungoren1, Feyzullah Besli1, Zulkif Tanriverdi1
1Department of Cardiology, Faculty of Medicine, Harran University, Sanliurfa, Turkey.
Insights
The caval index, measured via echocardiography, can predict contrast-induced nephropathy (CIN) after cardiac catheterization. A caval index of 41% or higher indicates a higher risk of developing CIN.
Area of Science:
- Cardiology
- Nephrology
- Medical Imaging
Background:
- Contrast-induced nephropathy (CIN) is a significant complication of cardiac catheterization.
- Patient volume status is crucial in CIN development and can be assessed noninvasively.
- Inferior vena cava (IVC) diameter measurements offer a potential method for volume status assessment.
Purpose of the Study:
- To evaluate the inferior vena cava (IVC) diameter as a predictor of CIN in patients undergoing cardiac catheterization.
- To determine if the caval index can identify patients at risk for CIN.
- To assess the independent predictive value of the caval index for CIN.
Main Methods:
- Prospective enrollment of 269 patients undergoing cardiac catheterization.
- Measurement of IVC inspiratory and expiratory diameters using transthoracic echocardiography.
- Calculation of the caval index (percentage decrease in IVC diameter during respiration) and definition of CIN (serum creatinine increase).
Main Results:
- CIN developed in 17.1% of patients.
- Patients with CIN had a significantly higher caval index (47% vs. 35%, P < 0.001).
- A caval index ≥ 41% independently predicted CIN development (OR: 3.367, P = 0.002).
Conclusions:
- The caval index is a simple, noninvasive echocardiographic marker.
- It serves as an independent predictor of post-procedural CIN.
- This marker can aid in identifying patients at risk for CIN following cardiac procedures.
Background:
Contrast-induced nephropathy (CIN) following cardiac catheterization remains a considerable clinic challenge. Volume status is very important in the development of CIN. It can be assessed noninvasively by measuring inferior vena cava (IVC) diameters. The aim of this study was to assess whether IVC can be used for prediction of CIN in patient undergoing cardiac catheterization.
Methods:
A total of 269 patients undergoing cardiac catheterization were prospectively enrolled in this study. IVC inspiratory and expiratory diameters were measured by transthoracic echocardiography. Caval index was calculated as the percentage decrease in the IVC diameter during respiration. CIN was defined as a ≥0.5 mg/dL and/or a ≥25% increase in serum creatinine within 72 hour post-procedure.
Results:
Contrast-induced nephropathy developed in 46 (17.1%) patients after cardiac catheterization. Caval index was significantly higher in patients with CIN than in patients without CIN (47% [40-64] vs 35% [26-50], P < 0.001). In addition, the used contrast volume (145 [90-217] vs 70 [60-100], P < 0.001) and the frequency of percutaneous coronary intervention (50% vs 17.9%, P < 0.001) were significantly higher in patients with CIN than in patients without CIN. In receiver operating characteristic (ROC) curve analysis, caval index ≥ 41% predicted CIN with a specificity of 69% and sensitivity of 72%. Multivariate analysis indicated that caval index ≥ 41% was an independent predictor of post-procedural CIN development (OR: 3.367, 95% CI: 1.574-7.203, P = 0.002).
Conclusions:
Caval index, a simple and noninvasive echocardiographic marker, is an independent predictor of post-procedural CIN development in patients undergoing cardiac catheterization.
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