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Coculture System with an Organotypic Brain Slice and 3D Spheroid of Carcinoma Cells

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Erysipelatoid Carcinoma.

Thiago Sande Miguel¹, Daniel Almeida da Costa¹, Ana Paula Moura de Almeida²

¹Medical School of Valença - Rio de Janeiro, RJ, Brasil.

Revista Da Associacao Medica Brasileira (1992)

|October 11, 2018

Summary

This summary is machine-generated.

Erysipeloid Carcinoma (EC), a rare skin metastasis often linked to breast cancer, presents as an inflamed, red patch near the mastectomy site. This case highlights EC diagnosis in a patient with a history of breast cancer.

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Area of Science:

Oncology
Dermatology
Pathology

Background:

Erysipeloid Carcinoma (EC), or Inflammatory Metastatic Carcinoma, is a rare cutaneous metastasis.
It is frequently associated with underlying internal malignancies, particularly breast cancer.

Observation:

EC clinically manifests as a well-demarcated, erythematous plaque, mimicking infectious conditions like erysipelas or cellulitis.
Lesions often appear acutely or subacutely, presenting as a warm, sometimes painful, erythematous plaque.
The location is typically near the primary tumor site, commonly on the chest wall post-mastectomy for breast cancer.

Findings:

This report details a case of a 75-year-old patient with a 3-year history of ductal infiltrated carcinoma.
The patient presented with an acute, erythematous, and infiltrated plaque in the area of a prior mastectomy.
The final diagnosis confirmed Erysipeloid Carcinoma.

Implications:

Accurate diagnosis of EC is crucial to differentiate it from infectious processes, ensuring appropriate oncological management.
Recognizing EC's presentation is vital for early detection of metastatic disease in cancer patients.
This case underscores the importance of considering EC in the differential diagnosis of inflammatory skin lesions in post-mastectomy patients.