Related Experiment Video
Updated: Feb 4, 2026

06:13
The Intra-Aortic Balloon Pump
Published on: February 5, 2021
24.7K
[Intraaortic Balloon Pumping(IABP) and Impella].
1Department of Cardiovascular Surgery, Osaka University Graduate School of Medicine, Suita, Japan.
Kyobu Geka. the Japanese Journal of Thoracic Surgery
|October 13, 2018
Summary
Less invasive mechanical circulatory support devices like the Impella pump show promise. These advanced technologies improve cardiac output and function, aiding patient recovery and rehabilitation.
Area of Science:
- Cardiology
- Medical Devices
- Thoracic Surgery
Background:
- Intraaortic balloon pumping (IABP) is a widely used, established cardiac support device in Japan.
- Less invasive approaches for IABP via the axillary artery allow for patient ambulation and rehabilitation.
- Impella, a novel microaxial blood pump, offers a less invasive option for left ventricular assistance.
Purpose of the Study:
- To evaluate the clinical outcomes of Impella use in patients requiring mechanical circulatory support.
- To assess the impact of Impella on cardiac output and cardiac function.
- To explore the potential role of advanced less invasive mechanical circulatory support in thoracic surgery and cardiology.
Main Methods:
- Retrospective analysis of 11 patients treated with Impella.
- Monitoring of cardiac output and cardiac function parameters.
- Assessment of patient recovery and cardiac recovery.
Main Results:
- Impella use led to improvements in cardiac output.
- Significant enhancement in cardiac function was observed.
- Cardiac recovery occurred in 5 out of 11 patients.
- Less invasive approaches facilitated patient rehabilitation.
Conclusions:
- Impella demonstrates efficacy in improving cardiac performance and function.
- Mechanical circulatory support via less invasive methods can lead to cardiac recovery.
- Technological advancements in mechanical circulatory support are crucial for cardiology and thoracic surgery.
More Related Videos
Related Concept Videos
ATP Driven Pumps III: V-type Pumps
4.8K
V-type pumps are ATP-driven pumps found in the vacuolar membranes of plants, yeast, endosomal and lysosomal membranes of animal cells, plasma membranes of a few specialized eukaryotic cells, and some prokaryotes. They are also known as the V1Vo-ATPase, that couple ATP hydrolysis to transport protons against a concentration gradient.
The peripheral or cytosolic V1 domain with eight subunits is involved in ATP hydrolysis. The integral or transmembrane V0 domain containing at least five subunits...
The peripheral or cytosolic V1 domain with eight subunits is involved in ATP hydrolysis. The integral or transmembrane V0 domain containing at least five subunits...
4.8K
ATP Driven Pumps II: P-type Pumps
6.4K
The P-type pumps are a large family of integral membrane transporter ATPases. They are divided into five major types based on substrate specificity, from I to V.
A typical P-type pump has three cytosolic domains: nucleotide-binding (N), phosphorylation (P), and activator (A) domains. These domains are connected to the membrane-spanning helices by short amino acid segments. ATP hydrolysis and covalent phosphoenzyme intermediate formation are crucial parts of the catalytic cycle. At the highly...
A typical P-type pump has three cytosolic domains: nucleotide-binding (N), phosphorylation (P), and activator (A) domains. These domains are connected to the membrane-spanning helices by short amino acid segments. ATP hydrolysis and covalent phosphoenzyme intermediate formation are crucial parts of the catalytic cycle. At the highly...
6.4K
Pumped Concrete
379
Concrete in large quantities can be pumped across long distances for placing in inaccessible sites. This system comprises a hopper that receives concrete from a mixer, a pump to propel the concrete, and pipelines that facilitate its delivery.
For direct-acting pumps, the concrete enters the pump via the inlet valve under the action of gravity and suction created by the movement of the piston. This concrete is then forced into the pipeline and out through the outlet valve by the forward movement...
For direct-acting pumps, the concrete enters the pump via the inlet valve under the action of gravity and suction created by the movement of the piston. This concrete is then forced into the pipeline and out through the outlet valve by the forward movement...
379
Refrigerators and Heat Pumps
3.0K
Refrigerators or heat pumps are heat engines operating in a reverse direction. For a refrigerator, the focus is on removing heat from a specific area, whereas, for a heat pump, the focus is on dumping heat into one particular area. A refrigerator (or heat pump) absorbs heat Qc from the cold reservoir at Kelvin temperature Tc and discards heat Qh to the hot reservoir at Kelvin temperature Th, while work W is done on the engine’s working substance.
A household refrigerator removes heat from...
A household refrigerator removes heat from...
3.0K
ATP Driven Pumps I: An Overview
9.9K
ATP-driven pumps, also known as transport ATPases, are integral membrane proteins. They have binding sites for ATP located on the membrane's cytosolic side and the ion-conducting domain in the transmembrane region. These pumps use the free energy released from ATP hydrolysis to move the solutes across cell membranes against an electrochemical gradient.
There are four main types of ATP-driven pumps - P-type, V-type, F-type, and ABC transporter. All these pumps are of varying complexities and...
There are four main types of ATP-driven pumps - P-type, V-type, F-type, and ABC transporter. All these pumps are of varying complexities and...
9.9K
Acid Suppressive Drugs for Peptic Ulcer Disease: Proton Pump Inhibitors
955
Peptic ulcers, often induced by H. pylori infections or NSAID usage, arise from disruptions in the delicate balance of gastric acid production. Peptic ulcers stem from heightened gastric acid levels due to H. pylori infections or NSAID use. The protective mucus layer diminishes in the presence of these factors, allowing gastric acid to erode the stomach lining and form ulcers.
Gastric acid, a potent cocktail of hydrogen and chloride ions, is produced in specialized parietal cells within the...
Gastric acid, a potent cocktail of hydrogen and chloride ions, is produced in specialized parietal cells within the...
955

