Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

568
Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
568
Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

490
Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
490
Cardiomyopathy IV: Restrictive Cardiomyopathy01:29

Cardiomyopathy IV: Restrictive Cardiomyopathy

538
Restrictive cardiomyopathy (RCM) is a rare heart muscle disease characterized by impaired ventricular filling due to stiffened ventricular walls, leading to significant diastolic dysfunction.EtiologyRestrictive cardiomyopathy can arise from both inherited and acquired diseases, many of which are systemic. It is categorized into four main types: infiltrative, storage, non-infiltrative, and endomyocardial diseases.Infiltrative diseases, such as amyloidosis, lead to RCM by depositing amyloid...
538
Cardiomyopathy V: Interprofessional Care01:29

Cardiomyopathy V: Interprofessional Care

442
Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
442
Cardiomyopathy I: Introduction and Classification01:25

Cardiomyopathy I: Introduction and Classification

605
Cardiomyopathy, or CMP, is a group of diseases affecting the myocardial structure, impairing its ability to pump blood effectively. This condition can lead to arrhythmias, heart failure, or sudden cardiac death.Cardiomyopathies are classified into primary and secondary categories:Primary Cardiomyopathy refers to conditions involving only the heart muscle that are often idiopathic (of unknown cause) or genetic. They primarily affect the myocardium without the involvement of other systemic...
605
Cardiomyopathy VI: Nursing Management01:29

Cardiomyopathy VI: Nursing Management

356
Assessment: Nursing management of patients with cardiomyopathy begins with a thorough assessment of the patient's history, including a family history of cardiomyopathy or sudden cardiac death, personal history of heart disease, hypertension, diabetes, and any alcohol consumption or drug use.During the physical examination, assess vital signs, look for signs of heart failure (such as edema, jugular venous distention, and cyanosis), auscultate for abnormal heart sounds (like murmurs and gallops),...
356

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Role of Cardiovascular Disease Journals in Reporting Sex and Gender in Research.

European journal of preventive cardiology·2025
Same author

The Role of Cardiovascular Disease Journals in Reporting Sex and Gender in Research.

European heart journal. Acute cardiovascular care·2025
Same author

The Role of Cardiovascular Disease Journals in Reporting Sex and Gender in Research.

European heart journal·2025
Same author

The Role of Cardiovascular Disease Journals in Reporting Sex and Gender in Research.

Journal of the American College of Cardiology·2025
Same author

Role of Cardiovascular Disease Journals in Reporting Sex and Gender in Research.

Circulation·2025
Same author

The Role of Cardiovascular Disease Journals in Reporting Sex and Gender in Research.

JAMA cardiology·2025
Same journal

The Harrowing Status of Research and Medical Practice in Countries Affected by War.

European cardiology·2026
Same journal

Intracardiac Thrombi in Behçet's Disease: Systematic Review of 218 Patients' Clinical Characteristics and Treatments.

European cardiology·2026
Same journal

Commissural and Coronary Alignment Strategies in Transcatheter Aortic Valve Replacement: Success Rate and Risks.

European cardiology·2026
Same journal

Myosin Inhibition in Non-obstructive Hypertrophic Cardiomyopathy: Lessons from ODYSSEY-HCM.

European cardiology·2026
Same journal

Cardiac Diseases in Sudan 1970-2025: Current Situation and Future Prospects.

European cardiology·2026
Same journal

Bidirectional Block Assessment Techniques During Cavotricuspid Isthmus Ablation: A Comprehensive Review.

European cardiology·2026
See all related articles

Related Experiment Video

Updated: Feb 4, 2026

Modeling and Evaluation of Murine Diabetic Cardiomyopathy Model
06:22

Modeling and Evaluation of Murine Diabetic Cardiomyopathy Model

Published on: November 29, 2024

1.5K

Takotsubo Cardiomyopathy.

Esha Sachdev1, C Noel Bairey Merz1, Puja K Mehta1

  • 1Barbra Streisand Women's Heart Center, Cedars-Sinai Heart Institute, Los Angeles, California, US.

European Cardiology
|October 13, 2018
PubMed
Summary
This summary is machine-generated.

Takotsubo cardiomyopathy (TTC) is a stress-induced heart condition mimicking heart attacks, particularly in post-menopausal women. Its exact cause remains unclear, but catecholamine surges and coronary dysfunction are implicated.

Keywords:
Mental stresscatecholaminewomen heart disease

More Related Videos

A Doxorubicin-Induced Murine Model of Dilated Cardiomyopathy In Vivo
05:14

A Doxorubicin-Induced Murine Model of Dilated Cardiomyopathy In Vivo

Published on: May 16, 2020

5.4K
Tachycardia-Induced Cardiomyopathy As a Chronic Heart Failure Model in Swine
10:08

Tachycardia-Induced Cardiomyopathy As a Chronic Heart Failure Model in Swine

Published on: February 17, 2018

14.0K

Related Experiment Videos

Last Updated: Feb 4, 2026

Modeling and Evaluation of Murine Diabetic Cardiomyopathy Model
06:22

Modeling and Evaluation of Murine Diabetic Cardiomyopathy Model

Published on: November 29, 2024

1.5K
A Doxorubicin-Induced Murine Model of Dilated Cardiomyopathy In Vivo
05:14

A Doxorubicin-Induced Murine Model of Dilated Cardiomyopathy In Vivo

Published on: May 16, 2020

5.4K
Tachycardia-Induced Cardiomyopathy As a Chronic Heart Failure Model in Swine
10:08

Tachycardia-Induced Cardiomyopathy As a Chronic Heart Failure Model in Swine

Published on: February 17, 2018

14.0K

Area of Science:

  • Cardiology
  • Internal Medicine

Background:

  • Takotsubo cardiomyopathy (TTC) is an acute, stress-induced heart condition.
  • It frequently affects post-menopausal women and mimics acute myocardial infarction.
  • Symptoms, ECG changes, and troponin elevations are indistinguishable from plaque rupture or coronary thrombosis.

Purpose of the Study:

  • To review the characteristic clinical presentation of Takotsubo cardiomyopathy.
  • To discuss the commonly proposed pathophysiological mechanisms of TTC.
  • To explore the reasons for TTC's higher prevalence in post-menopausal women.

Main Methods:

  • This is a review article.
  • It synthesizes current knowledge on TTC's clinical presentation and pathophysiology.
  • Diagnostic criteria, including coronary angiography findings, are discussed.

Main Results:

  • TTC presents with apical ballooning and basal hypercontractility, though other patterns exist.
  • Diagnosis requires absence of obstructive coronary artery disease.
  • Proposed mechanisms include catecholamine surge, coronary vasospasm, and microvascular dysfunction.

Conclusions:

  • The pathophysiology of TTC involves an abnormal myocardial response to catecholamine surges.
  • The high prevalence in post-menopausal women is not fully understood.
  • Treatment follows guidelines for acute coronary syndrome, myocardial infarction, and heart failure.