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Related Experiment Videos

SMART - Not Always Only "Stroke-Like".

Vanessa Haller1, David Dashti2, Nils Peters1

  • 1Department of Neurology and Stroke Center, University Hospital Basel, Basel, Switzerland.

Headache
|October 13, 2018
PubMed
Summary

Stroke-like migraine attacks after radiation therapy (SMART) can mimic migraine but may also involve ischemic stroke. This rare syndrome can lead to poor outcomes, even after initial improvement.

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Area of Science:

  • Neurology
  • Radiation Oncology
  • Neuroscience

Background:

  • Stroke-like migraine attacks after radiation therapy (SMART) is a delayed syndrome following brain radiation.
  • It is a critical differential diagnosis for migraine in patients who have undergone radiation therapy.

Observation:

  • SMART typically presents with migraine-like headaches.
  • Focal neurological deficits and seizures can also occur.
  • The condition is generally considered reversible, hence the term 'stroke-like'.

Findings:

  • This case highlights that ischemic stroke can be associated with SMART.
  • Such complications can lead to an unfavorable clinical course.
  • Even patients experiencing prior remission may develop stroke.
Keywords:
MRISMARTmigraineradiationseizurestroke

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Implications:

  • SMART requires careful consideration in patients with a history of brain radiation presenting with neurological symptoms.
  • The potential for associated ischemic stroke necessitates vigilant monitoring and management.
  • This underscores the importance of recognizing SMART as a potentially serious condition beyond reversible migraine-like symptoms.