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09:02
A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
Published on: February 2, 2021
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BILATERAL ACUTE RETINAL NECROSIS: A Case Series.
Boya Lei1, Rui Jiang1, Zhujian Wang1
1Department of Ophthalmology, Eye and ENT Hospital of Fudan University, Shanghai, China.
Retina (Philadelphia, Pa.)
|October 13, 2018
Summary
Bilateral acute retinal necrosis often affects the second eye within months, but can occur years later. The later-affected eye shows less severe necrosis and detachment, leading to better visual outcomes.
Area of Science:
- Ophthalmology
- Retinal Diseases
- Infectious Diseases
Background:
- Bilateral acute retinal necrosis (BARN) is a severe intraocular inflammatory condition.
- Understanding the temporal progression and clinical features of BARN is crucial for patient management.
Purpose of the Study:
- To investigate the clinical characteristics of BARN.
- To evaluate the visual outcomes in patients with BARN.
Main Methods:
- Retrospective review of medical records of 30 patients diagnosed with BARN.
- Analysis of disease onset, severity, retinal detachment, and visual acuity.
Main Results:
- Most patients developed BARN in the contralateral eye within 5 months; some cases occurred after 2 years.
- Initially affected eyes showed more extensive necrosis (>180°) and higher rates of retinal detachment.
- Visual acuity in initially affected eyes worsened, while it improved significantly in later-affected eyes.
Conclusions:
- BARN typically manifests in the fellow eye within months, but delayed onset is possible.
- The later-affected eye generally experiences less inflammation and retinal detachment, resulting in a more favorable visual prognosis.
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