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Updated: Feb 4, 2026

Testing the Vascular Invasive Ability of Cancer Cells in Zebrafish Danio Rerio
Published on: November 3, 2016
[Vascular Complications Of Cancer Chemotherapy]
Y N Belenkov1, E V Privalova1, M V Kozhevnikova1
1I.M. Sechenov First Moscow State Medical University (Sechenov University).
Abstract:
Development and use of new anticancer drugs has resulted in the improving of 5‑year survival rates in patients with cancer. However, many of the modern chemotherapies are associated with cardiovascular toxicities that increases cardiovascular risk in cancer patients, including hypertension, heart failure, thrombosis and thromboembolism, cardiomyopathy, and arrhythmias. These side effects limitation restrict treatment options and farther perspectives. With increasing use of modern chemotherapies and prolongation of the cancer patients survival, the incidence of cardiovascular disease in this patient population will continue to increase. Accordingly, careful assessment and management of cardiovascular risk factors in cancer patients by oncologists and cardiologists working together is essential for optimal care.
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