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Updated: Feb 4, 2026

Solid Plate-based Dietary Restriction in Caenorhabditis elegans
Published on: May 28, 2011
Influence of Dietary Restriction on Irritable Bowel Syndrome
1Department of Gastroenterology and Hepatology, Digestive Diseases and Surgical Institute, Cleveland Clinic, Cleveland, OH, USA.
Abstract:
Up to two-thirds of patients with IBS attribute their gastrointestinal symptoms to food. The therapeutic focus of IBS has been to alleviate gastrointestinal symptoms, approached by pharmaceutical and non-pharmaceutical treatments. Although the most traditional approach has involved the use of medications such as bulking agents, anticholinergics, antispasmodics, and antidiarrheals, unfortunately these are only modestly effective and patients are left with a small menu of successful pharmacologic agents. These treatments, however, are not always enough to alleviate symptoms. Alternative approaches have therefore been tried, including dietary manipulation. This article aims to review dietary restrictions as a non-pharmaceutical management approach for IBS, covering literature on various dietary triggers and the impact of dietary manipulation on gastrointestinal symptoms.
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