Related Experiment Video

Updated: Apr 18, 2026

An Ex vivo Assay to Study Candida albicans Hyphal Morphogenesis in the Gastrointestinal Tract
07:42

An Ex vivo Assay to Study Candida albicans Hyphal Morphogenesis in the Gastrointestinal Tract

Published on: July 1, 2020

6.0K

Candida Enteritis Diagnoses in the United States: Prevalence and Clinical Insights from a Large Commercial Insurance

Kaitlin Benedict1, Jeremy A W Gold2, Mark Pimentel3

  • 1Mycotic Diseases Branch, Division of Foodborne, Waterborne, and Environmental Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road NE, Mailstop H24-9, Atlanta, GA, USA. jsy8@cdc.gov.

Digestive Diseases and Sciences
|April 16, 2026
PubMed
Abstract

Insights

Candida overgrowth in the small intestine is challenging to diagnose, often presenting with non-specific gastrointestinal symptoms. Increased provider awareness for intestinal Candida is needed for better diagnosis and treatment.

Area of Science:

  • Gastroenterology
  • Mycology
  • Epidemiology

Background:

  • Small intestinal Candida overgrowth presents non-specific gastrointestinal symptoms.
  • Differential diagnosis is challenging due to symptom overlap with other conditions.

Purpose of the Study:

  • To characterize patients diagnosed with Candida enteritis.
  • Utilized a large US commercial health insurance claims dataset.

Main Methods:

  • Data sourced from Merative™ MarketScan® Commercial/Medicare Database.
  • Identified patients with Candida enteritis diagnosis codes.

Main Results:

  • 3,710 patients identified with Candida enteritis.
  • Higher rates observed in women, ages 35-44, and in the West region.
  • Common symptoms include fatigue (44%) and abdominal pain (26%).
  • Low utilization of esophagogastroduodenoscopy (6%) and moderate use of antifungal therapy (38%).

Conclusions:

  • Healthcare provider awareness regarding intestinal Candida overgrowth diagnosis and treatment requires enhancement.
  • Improved diagnostic and therapeutic strategies are necessary.
Keywords:
CandidaEnteritisFungiHealthInsuranceIntestine, smallYeasts

More Related Videos

Author Spotlight: Oral Candida Diagnosis to Advance Clinical Treatment Regimen for pSS Patients05:26

Author Spotlight: Oral Candida Diagnosis to Advance Clinical Treatment Regimen for pSS Patients

Published on: March 1, 2024

2.3K
Modeling Mucosal Candidiasis in Larval Zebrafish by Swimbladder Injection06:28

Modeling Mucosal Candidiasis in Larval Zebrafish by Swimbladder Injection

Published on: November 27, 2014

10.7K

Related Concept Videos

Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies01:28

Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies

Peptic ulcer disease (PUD) presents with diverse symptoms depending on the location and severity of the ulcer. Clinical manifestations of peptic ulcer include dull pain and a burning sensation in the mid-epigastric region.
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
863
Inflammatory Bowel Disease IV: Clinical Manifestations01:20

Inflammatory Bowel Disease IV: Clinical Manifestations

Inflammatory bowel disease (IBD) encompasses two major chronic disorders—ulcerative colitis and Crohn’s disease—each characterized by relapsing episodes of gastrointestinal inflammation. Although they share certain clinical features, their patterns of involvement and manifestations differ in ways that aid diagnosis and guide management.Ulcerative ColitisUlcerative colitis is limited to the colon and rectum and involves continuous inflammation of the mucosal layer. The...
1
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation01:30

Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation

Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
1.1K
Peptic Ulcer Disease III: Clinical Manifestations and Complications01:25

Peptic Ulcer Disease III: Clinical Manifestations and Complications

Duodenal UlcersDuodenal ulcers are the most common form of peptic ulcer disease, presenting with chronic, intermittent epigastric pain. Pain typically appears 2–3 hours after meals, especially when the stomach is empty, often waking patients at night. It is characteristically relieved by food or antacids (“pain–food–relief”). Some patients remain asymptomatic until complications like bleeding or perforation emerge, particularly with NSAID or anticoagulant...
2
Fungal Phylum Microsporidia01:28

Fungal Phylum Microsporidia

Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
767
Prevalence and Incidence01:08

Prevalence and Incidence

In statistical epidemiology and health sciences, two essential metrics—prevalence and incidence—are fundamental for understanding disease dynamics within a population. These measures enable public health officials, epidemiologists, and researchers to assess the burden of diseases, allocate resources effectively, and design impactful public health policies and interventions.
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
2.4K