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Updated: Feb 4, 2026

Porcine Model of Infrarenal Abdominal Aortic Aneurysm
Published on: November 21, 2019
[Prevalence of abdominal aortic aneurysm in patients with chronic obstructive pulmonary disease]
Manuel Silva1, Joana Ferreira2, Sandrina Braga3
1Escola de Medicina, Universidade do Minho, Braga, Portugal.
Introduction:
The association of the abdominal aortic aneurysm (AAA) to the chronic obstructive pulmonary disease (COPD) is questionable. Both entities share the same risk factors and physiopathology, which is based on a persistent pro- -inflammatory response, proteolysis and excessive extracellular matrix turnover.
Objectives:
To determine the AAA prevalence in a sample of patients with COPD.
Methods:
Identification of patients with COPD and abdominal CT, hospitalized in a level 2 hospital between January 2015 and December 2016.
Results:
In a sample with 100 patients, 5 presented an AAA. There were no significant differences between patients with and without AAA regarding gender (100% versus 69,5% male), age (74,80±6,22 versus 71,23±12,36 years), comorbidities (myocardial infarction 0% versus 1,1%; stroke 0% versus 10,5%), cardiovascular risk factors (diabetes mellitus 20% versus 23,2%; hypertension 80% versus 50,5%) and spirometric results. Patients with AAA were significantly more medicated with acetylsalicylic acid and had more aortic thrombi (P=0,031 and P=0,002, respectively). No correlation was found between the aortic size and the forced expiratory flow in one second values.
Discussion:
The AAA prevalence of our sample was 5%, twice the described for the Portuguese population (2,37%). This is the first study conducted in Portugal to determine the AAA prevalence in COPD patients.
Conclusion:
The study of the relationship between both diseases could contribute to a more effective screening of AAA, by determining a group with increased risk, which could lead to a reduction of the mortality rates associated with the ruptured aneurysm.
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