Natural Course of Myxopapillary Ependymoma: Unusual Case Report and Review of Literature
Serhat Pusat1, Yahya Cem Erbaş2, Selçuk Göçmen3
1Sultan Abdulhamid Training and Research Hospital, Department of Neurosurgery, Istanbul, Turkey.
Background:
Spinal cord ependymomas are the most frequent primary intramedullary tumors of the cord in middle age (40-60 years of age). Myxopapillary ependymomas are low-incidence tumors and occur in the cauda equina and conus medullaris. They are typically described as fleshy, sausage-shaped, vascular lesions.
Case Description:
In this report, we present a 36-year-old woman who was seen in another hospital with complaints of back pain radiating into both legs 5 years ago. Magnetic resonance imaging (MRI) examinations revealed a lesion releated to the spinal cord. At that point, the patient refused the proposed surgical treatment. Five years later, the patient was referred to our clinic with advancement of the complaint to paraparesis. The new MRI showed an intradural mass at the level of T11 and S1. We performed a total intradural tumor resection. Histopathologic examination revealed a myxopapillary ependymoma.
Conclusions:
Myxopapillary ependymomas grow slowly and are well defined by MRI. Advancements in radiologic technology and surgical equipment have allowed this tumor type to be treated successfully. Unfortunately, if untreated, these lesions have poor prognosis and result in clinical symptoms such as paraparesis. Surgical treatment of these lesions using total resection was performed total resection and was associated with an excellent postoperative outcome. We highlight the natural course of myxopapillary ependymomas.
Insights
Myxopapillary ependymomas are slow-growing spinal cord tumors. Early diagnosis and surgical resection lead to excellent outcomes, while untreated lesions can cause severe neurological deficits like paraparesis.
Area of Science:
- Neurosurgery
- Neuropathology
- Spinal Oncology
Background:
- Spinal cord ependymomas are common intramedullary tumors in middle-aged adults.
- Myxopapillary ependymomas, a rare subtype, typically affect the cauda equina and conus medullaris.
- These tumors are characterized by slow growth and distinct vascular features.
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