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Antibiotic Dereplication Using the Antibiotic Resistance Platform
Published on: October 17, 2019
Are Perioperative Antibiotics Necessary During Direct Microlaryngoscopy?
Megan Yetzke1, Richard Heyes2, Natasha Nakra3
1University Voice and Swallowing Center, Department of Otolaryngology-Head and Neck Surgery, University of California, Irvine School of Medicine, Irvine, California.
Objectives/Hypothesis:
There are currently no established recommendations for the use of perioperative antibiotics (PAs) to prevent surgical site infections (SSIs) for direct microlaryngoscopy (DML). This study examined the incidence of SSI in patients undergoing DML with and without PAs.
Study Design:
Retrospective, multi-institutional chart review.
Methods:
A retrospective, multi-institutional chart review was performed at four tertiary referral academic medical centers. Patients undergoing DML from 2010 to 2017 were identified using Current Procedural Terminology codes. Medical records of patients undergoing DML with biopsy, microsurgery, laser ablation, or vocal fold injection who had adequate follow-up were reviewed. Procedures with significant cartilage destruction, concurrent open surgery, or esophageal surgery were excluded. Data recorded included age, gender, pacemaker history, American Society of Anesthesiologists class, wound class, indication for surgery, use of laser, complications, emergency room visits, hospitalizations, pain, fever, and postoperative steroid and antibiotic prescriptions. Presence or absence of SSIs was evaluated by a fellowship-trained laryngologist.
Results:
There were 834 patients who met inclusion criteria. Of those, 698 did not receive PAs and 136 received PAs. The median age of patients was 54 years of age in the PA group and 57.5 years of age in the non-PA group, and all cases were recorded as wound class II. Overall, 58% of surgeries involved use of carbon dioxide or potassium-titanyl-phosphate laser. Only one SSI was reported on follow-up in a patient who did receive PAs.
Conclusions:
SSIs are exceedingly rare following DML. PA use is not indicated for routine DML.
Level Of Evidence:
4 Laryngoscope, 128:2838-2843, 2018.
Insights
Perioperative antibiotics are not recommended for direct microlaryngoscopy (DML) procedures. Surgical site infections (SSIs) are rare after DML, even without antibiotic use.
Area of Science:
- Otolaryngology
- Surgical Infections
Background:
- Direct microlaryngoscopy (DML) is a common procedure.
- There are no current guidelines for perioperative antibiotic (PA) use to prevent surgical site infections (SSIs) in DML.
Purpose of the Study:
- To determine the incidence of SSIs in patients undergoing DML.
- To evaluate the necessity of PAs for preventing SSIs in DML.
Main Methods:
- Retrospective, multi-institutional chart review of 834 patients undergoing DML.
- Data collected included patient demographics, surgical details, and postoperative outcomes.
- SSIs were assessed by a fellowship-trained laryngologist.
Main Results:
- Only one SSI was reported among 834 patients.
- The single SSI occurred in a patient who received PAs.
- Most surgeries involved laser use and were classified as wound class II.
Conclusions:
- Surgical site infections are very rare following DML.
- Perioperative antibiotic use is not indicated for routine DML procedures.
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