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Updated: Feb 3, 2026

Application of Deep Learning-Based Medical Image Segmentation via Orbital Computed Tomography
Published on: November 30, 2022
Split Bregman method based level set formulations for segmentation and correction with application to MR images and
Yunyun Yang1, Dongcai Tian1, Wenjing Jia1
1School of Science, Harbin Institute of Technology, Shenzhen, China.
This study introduces an improved active contour model for segmenting magnetic resonance (MR) images, effectively addressing intensity inhomogeneity. The new model offers accurate segmentation and bias field correction for both grayscale and color MR images.
Area of Science:
- Medical Imaging
- Computer Vision
- Image Processing
Background:
- Magnetic Resonance (MR) imaging is crucial for clinical diagnosis, but image segmentation is challenging due to intensity inhomogeneity.
- Accurate and fast segmentation of MR images is vital for medical research.
Purpose of the Study:
- To develop an improved active contour model for accurate MR image segmentation and bias field correction.
- To enhance segmentation accuracy and efficiency by combining level set evolution (LSE) with the split Bregman method.
Main Methods:
- An improved active contour model integrating the level set evolution (LSE) model and the split Bregman method.
- Incorporation of a bias field correction into the energy functional to address image inhomogeneity.
- Application of two-phase, multi-phase, and vector-valued formulations to segment synthetic and real MR images.
Main Results:
- The proposed model achieved satisfactory segmentation and correction for both grayscale and color MR images.
- Demonstrated higher accuracy and superiority compared to the standard LSE model.
- Showcased robustness to noise and insensitivity to initial contour placement.
Conclusions:
- The improved active contour model effectively segments inhomogeneous MR images and provides corrected, homogeneous images.
- The split Bregman method accelerates the segmentation process, reducing computation time and iterations.
- The model offers a robust and accurate solution for MR image analysis in clinical medicine and research.
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