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Temporal (in)stability of suboptimal toe-brachial indices.
Robert Trevethan1, Sylvia McAra2
1Independent Academic Researcher and Author, Albury, NSW, Australia.
Foot (Edinburgh, Scotland)
|October 17, 2018
Summary
The toe-brachial index (TBI) shows significant fluctuations in individuals with suboptimal readings, potentially limiting its use for screening and monitoring peripheral artery disease.
Area of Science:
- Vascular Medicine
- Biomedical Engineering
Background:
- The toe-brachial index (TBI) is crucial for assessing peripheral artery disease (PAD).
- Effective use of TBI in screening, prognosis, and monitoring requires stable readings over time.
Purpose of the Study:
- To investigate the temporal stability of TBI in individuals with suboptimal baseline measurements.
- To determine if TBI readings exhibit significant fluctuations over a 6-month period.
Main Methods:
- TBI measurements were taken from 21 participants with suboptimal baseline TBI (≤0.65 or ≤0.85) using automated devices.
- Readings were collected at baseline, 2 months, and 6 months.
- Analysis focused on temporal stability of ipsilateral and contralateral TBI values.
Main Results:
- After excluding participants with extreme fluctuations, 16 individuals were analyzed.
- Significant ipsilateral TBI changes (≥0.10) occurred in 11 participants within 2 and 6 months.
- Contralateral TBI differences (≥0.10) were observed in 5 participants (2 months) and 9 participants (6 months).
Conclusions:
- Suboptimal TBI readings can exhibit considerable ipsilateral and contralateral inconsistency.
- This variability may compromise the reliability of TBI for clinical screening, prognostic, and monitoring applications.
- Standardized protocols and alternative assessment methods are recommended to enhance TBI's clinical utility.
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