Colorimetric sensor for the detection of H₂S and its application in molecular half-subtractor

Azine based new colorimetric sensor 1 for the detection of gasotransmitter H₂S has been reported. Sensor 1 used to detect the H₂S with a remarkable red shift of 105 nm in the absorption spectra with a colour change from light yellow to brown red. Importantly, rare example of azine derivative has been used as a colorimetric probe for H₂S detection using deprotonation mechanism. H₂S induced deprotonation of one of the -OH proton followed by a change in resonance of 1 is responsible for the ratiometric spectral and colour change. The detection response was quick and the LOD calculated as 18.2 μM. Sensor 1 was also explored in the detection of H₂S in biological fluids such as human serum and mouse serum. Moreover, for the first time, we have shown the applicability of H₂S for the construction of half subtractor molecular logic gate.