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Updated: Feb 3, 2026

Rapid Screening of HIV Reverse Transcriptase and Integrase Inhibitors
Published on: April 9, 2014
A System-Level Approach to Improve HIV Screening in an Urban Pediatric Primary Care Setting
Renata Arrington-Sanders1, Noah J Wheeler2, Pamela Matson2
1Division of Pediatrics and Adolescent Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland rarring3@jhmi.edu.
Implementing rapid HIV screening significantly boosted testing rates and ensured more youth received results promptly. This approach effectively increases HIV testing and care access for adolescents.
Area of Science:
- Public Health
- Infectious Disease Prevention
- Adolescent Health
Background:
- Many adolescents living with HIV are unaware of their status, despite recommendations for universal screening.
- Pediatric primary care settings face challenges in testing at-risk youth for HIV.
- Current HIV screening rates among at-risk youth in pediatric primary care are suboptimal.
Purpose of the Study:
- To evaluate the impact of rapid HIV screening implementation on screening rates.
- To assess the effect of rapid HIV screening on HIV test result receipt among youth.
- To improve HIV service delivery to adolescents in primary care settings.
Main Methods:
- A quality improvement initiative using a plan-do-study-act model over four cycles.
- Included 4433 eligible patients aged 13-25 years for HIV screening.
- Logistic regression and statistical process control charts analyzed screening rates and rapid test utilization.
Main Results:
- HIV screening rates increased from a baseline of 29.6% to 82.7% by cycle 4.
- Rapid screening accounted for 90.4% of all HIV tests conducted.
- Same-day result receipt was higher with rapid screening, and five HIV-positive patients were linked to care.
Conclusions:
- Rapid HIV screening, coupled with system modifications, substantially enhanced screening rates and result delivery.
- This intervention proves effective in delivering essential HIV services to youth.
- The study highlights the success of rapid HIV testing in pediatric primary care settings.
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