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Hemicrania Continua: a Clinical Perspective on Diagnosis and Management

Amit Mehta1, Priyanka Chilakamarri2, Adeel Zubair2

  • 1Department of Neurology, Yale School of Medicine, New Haven, CT, USA. ammehta9@gmail.com.

Current Neurology and Neuroscience Reports
|October 18, 2018
PubMed

Insights

Hemicrania Continua (HC) is a persistent, side-locked headache. Recent research reviews its diagnosis and management, highlighting potential underdiagnosis and the need for more treatment evidence.

Area of Science:

  • Neurology
  • Headache Medicine

Background:

  • Hemicrania Continua (HC) presents as a daily, persistent headache with unilateral pain.
  • Associated autonomic symptoms include lacrimation, nasal congestion, and ptosis.

Purpose of the Study:

  • To review recent research on the diagnosis and clinical management of Hemicrania Continua.
  • To discuss the classification of HC within Trigeminal Autonomic Cephalalgias (TACs).

Main Methods:

  • Review of functional imaging studies.
  • Analysis of recent clinical research on diagnosis and management.

Main Results:

  • Functional imaging reveals activation of subcortical structures like the posterior hypothalamus and dorsal rostral pons.
  • This activation pattern supports HC's classification as a TAC due to trigeminal autonomic reflex disinhibition.
  • Promising treatments are identified, but require further evidence for standardization.

Conclusions:

  • Hemicrania Continua is a potentially underdiagnosed primary headache disorder.
  • Further research is needed to establish evidence-based treatment standards for HC.
Abstract

Keywords:
HeadacheHemicrania continuaIndomethacinTrigeminal autonomic CephalgiaUnilateral headache

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