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Published on: August 25, 2020
Obesity and childhood asthma
1Division of Allergy/Immunology and Pulmonary Medicine, Duke Children's Hospital and Health Center, MSRB-1 203 Research Drive Rm 127, Durham, North Carolina, USA.
Insights
Childhood obesity is linked to new asthma cases and more severe symptoms. Understanding this connection is key for effective asthma management in children, considering individual needs and interactions between conditions.
Area of Science:
- Pediatric Pulmonology
- Environmental Health
- Epidemiology
Background:
- Asthma is a chronic airway disease affecting children's quality of life.
- Childhood obesity is a growing concern, with emerging links to asthma development and severity.
- The interplay between obesity and asthma in pediatric populations requires further investigation.
Purpose of the Study:
- To review the current understanding of obesity-related asthma in children.
- To explore the epidemiology, clinical characteristics, and management of this comorbidity.
- To synthesize existing knowledge on how obesity influences asthma inception and control.
Main Methods:
- Literature review of epidemiological studies.
- Analysis of clinical characteristics in children with comorbid asthma and obesity.
- Synthesis of current management strategies and guidelines.
Main Results:
- The relationship between childhood obesity and incident asthma is complex, influenced by early life factors, growth patterns, and genetics.
- Children with both obesity and asthma exhibit varied and evolving phenotypic characteristics.
- Effective management requires an individualized approach, acknowledging the interaction between obesity and asthma.
Conclusions:
- Further research is needed to fully elucidate the mechanisms linking childhood obesity to asthma.
- Personalized treatment plans are crucial for children with comorbid obesity and asthma.
- Understanding the bidirectional relationship is essential for improving health outcomes.
Purpose Of Review:
Asthma is a common chronic disease of the airways characterized by recurrent respiratory symptoms, bronchoreactivity, and airway inflammation. The high toll on quality of life has led to sustained efforts to understand the factors leading to asthma inception and poor disease control. Obesity is another increasingly common pediatric disease, which appears to increase the risk for incident asthma and worsened disease severity. Currently, our understanding of how obesity affects asthma risk and affects its phenotypic characteristics remains incomplete. The current review describes our current understanding of the epidemiology, clinical characteristics, and management considerations of obesity-related asthma in children.
Recent Findings:
The epidemiologic relationship between obesity in children and incident asthma remains confusing despite numerous longitudinal cohort studies, and appears to be influenced by early life exposures, patterns of somatic growth and underlying familial risks of allergic disease. Children with comorbid obesity and asthma demonstrate diverse phenotypic characteristics which are still becoming clear.
Summary:
Like any child with asthma, a child with comorbid obesity requires an individualized approach adhering to current best-practice guidelines and an understanding of how obesity and asthma may interact.
Related Concept Videos
Obesity
Asthma-I: Introduction
Asthma-III: Symptoms and Complications
Classification of Asthma
Asthma-IV: Diagnostic and Management
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Asthma: Pathogenesis and Management
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma-II: Pathophysiology and Classification
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:

