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A New SITA Perimetric Threshold Testing Algorithm: Construction and a Multicenter Clinical Study.

Anders Heijl1, Vincent Michael Patella2, Luke X Chong3

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PubMed
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The new Swedish Interactive Thresholding Algorithm (SITA) Faster significantly reduces visual field test time compared to SITA Fast and SITA Standard. It provides comparable results to SITA Fast, making it an efficient alternative for glaucoma testing.

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Area of Science:

  • Ophthalmology
  • Visual Psychophysics

Background:

  • Threshold visual field testing is crucial for diagnosing and monitoring glaucoma.
  • Existing algorithms like Swedish Interactive Thresholding Algorithm (SITA) Fast and SITA Standard have varying test durations.
  • There is a need for faster, yet accurate, visual field testing strategies.

Purpose of the Study:

  • To introduce and evaluate a novel, time-saving visual field testing strategy: Swedish Interactive Thresholding Algorithm (SITA) Faster.
  • To compare the performance of SITA Faster against SITA Fast and SITA Standard in terms of test time and diagnostic validity.

Main Methods:

  • A prospective study involving 126 glaucoma and glaucoma suspect patients across five centers.
  • Each patient underwent visual field testing with SITA Faster, SITA Fast, and SITA Standard on one eye over two visits.
  • Key outcomes measured included test duration, mean deviation, visual field index (VFI), significant test points, and test-retest variability.

Main Results:

  • SITA Faster demonstrated significantly shorter test times: 171.9 seconds compared to 247.0 seconds for SITA Fast and 369.5 seconds for SITA Standard (P < .001).
  • Test times were reduced by 30.4% with SITA Faster versus SITA Fast and 53.5% versus SITA Standard.
  • Mean deviation and visual field index (VFI) were comparable between SITA Faster and SITA Fast, with minor differences observed compared to SITA Standard, similar to previous SITA Fast vs. SITA Standard findings.
  • All three strategies exhibited similar test-retest variability.

Conclusions:

  • SITA Faster offers substantial time savings in visual field testing.
  • The diagnostic results from SITA Faster are highly consistent with SITA Fast.
  • SITA Faster represents a clinically valid and efficient advancement for threshold visual field testing in glaucoma management.