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Analysis of Interactions between Endobiotics and Human Gut Microbiota Using In Vitro Bath Fermentation Systems
Published on: August 23, 2019
Ginsenosides, catechins, quercetin and gut microbiota: Current evidence of challenging interactions
Rosaria Santangelo1, Andrea Silvestrini2, Cesare Mancuso3
1Institute of Microbiology, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma - Università Cattolica del Sacro Cuore, Largo F. Vito, 1, 00168, Roma, Italy.
Abstract:
Recent studies have shown the role of gut microbiota in favoring the absorption of herbal products and the transformation of their active principles into metabolites endowed with biological activity. This review focuses on the evidence supporting the changes occurring, after metabolic reactions by specific bacteria that colonize the human gut, to ginseng-derived ginsenosides, green tea-derived catechins, and quercetin, this latter being a flavonoid aglycon bound to sugars and abundant in some vegetables and roots. Furthermore, the results of several studies demonstrating the potential beneficial effects of the active metabolites generated by these biotransformations on ginsenosides, catechins and quercetin will be reported.
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