"Three in One" - Polyautoimmunity with Multiple Autoimmune Syndrome

Autoimmune disease (AD) may well start off as a single diagnosis and over the years develop into polyautoimmunity and even multiple autoimmune syndromes (MAS) seen in the same patient, as new clinical symptoms and laboratory finding show up in the course of disease. We present a case of MAS who was initially diagnosed to have autoimmune thyroid disease (AITD) - hypothyroidism. She was then evaluated for persistent mild to moderate iron deficiency anemia, unintentional weight loss along with skin rash and diagnosed to have celiac disease and undifferentiated connective tissue disease (uCTD).