Related Experiment Video
Updated: Feb 3, 2026

High Throughput In Vitro Assessment of Latency Reversing Agents on HIV Transcription and Splicing
Published on: January 22, 2019
Common Reversal Agents/Antidotes in Small Animal Poisoning
1ASPCA Animal Poison Control Center, 1717 South Philo Road, Suite 36, Urbana, IL 61802, USA; Global Pharmacovigilance, Zoetis, 333 Portage Street, Kalamazoo, MI 49007-9970, USA.
Abstract:
This article provides a quick source of information for practicing veterinarians for using various antidotes in small animal poisoning cases. For easy access, this information is included in the form of a table. The first column includes common names and/or brand names of different antidotes. In the second column, names of different toxicants or indications for which these antidotes can be used are described. The third column is the comment section that briefly describes salient points or cautions for using these antidotes.
Related Concept Videos
Anticholinesterase Agents: Poisoning and Treatment
Irreversible agents form a strong bond with the cholinesterase enzyme, making it inactive. The breakdown of the phosphorylated enzyme is...
Antidotes
Specific antidotes operate by inhibiting the enzymes that control biochemical pathways, reducing the production of harmful metabolites.
An example of an antidote is atropine, which counteracts the detrimental effects of cholinesterase inhibitors. It achieves this by deactivating muscarinic receptors,...
Local Anesthetics: Common Agents and Their Applications
Cocaine is an ester of benzoic acid and methylecgogine. It is used to anesthetize and vasoconstrict locally. Currently, it is used primarily for topical applications. It is beneficial for surgeries on the upper respiratory tract, providing anesthesia and shrinking the mucosa. Cocaine in the form of cocaine hydrochloride is...
Enhanced Elimination of Poison
Antidotes serve a crucial role in counteracting the effects of poison by inhibiting enzymes responsible for producing harmful drug metabolites. In some cases, these toxic metabolites can be neutralized by endogenous cosubstrates, which are maintained at specific concentrations to prevent interaction with cellular macromolecules and subsequent cell death.
Renal excretion is the...
Prevention of Further Absorption of Poison
Common Ion Effect

