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Insights into medical management of pediatric intestinal failure

Stephanie B Oliveira1, Conrad R Cole1

  • 1Division of Gastroenterology, Hepatology and Nutrition Cincinnati Children's Hospital Medical Center, MLC 2010, 3333 Burnet Avenue, Cincinnati, OH 45229, United States; Department of Pediatrics, College of Medicine, University of Cincinnati, United States.

Seminars in Pediatric Surgery
|October 22, 2018
PubMed

Insights

Specialized teams and advanced therapies improve outcomes for children with intestinal failure. Key strategies include nutritional support, bowel adaptation enhancement, and central line care to reduce complications.

Area of Science:

  • Pediatric Gastroenterology
  • Clinical Nutrition
  • Intestinal Rehabilitation

Background:

  • Intestinal failure in children presents complex management challenges.
  • Outcomes have historically been limited but are improving.
  • Multidisciplinary approaches are crucial for effective care.

Purpose of the Study:

  • To review current medical management strategies for pediatric intestinal failure.
  • To highlight advancements in nutritional support and complication reduction.
  • To provide insights into evolving therapeutic options.

Main Methods:

  • Review of current literature on pediatric intestinal failure management.
  • Analysis of key therapeutic interventions including nutritional support and pharmacotherapy.
  • Examination of strategies for preventing and managing complications.

Main Results:

  • Specialized pediatric intestinal failure teams significantly improve patient outcomes.
  • Adequate fluid, electrolyte, and caloric provision are essential for growth and development.
  • Parenteral nutrition modifications and central line care bundles reduce liver disease and infections.

Conclusions:

  • Multidisciplinary team management is the cornerstone of successful pediatric intestinal failure care.
  • Advances in parenteral nutrition and infection prevention are critical.
  • Ongoing research and therapeutic evolution continue to enhance long-term outcomes for affected children.

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