Related Experiment Video
Updated: Feb 3, 2026

Enhanced Genetic Analysis of Single Human Bioparticles Recovered by Simplified Micromanipulation from Forensic ‘Touch DNA’ Evidence
Published on: March 9, 2015
Microhaplotypes in forensic genetics
Fabio Oldoni1, Kenneth K Kidd2, Daniele Podini1
1Department of Forensic Sciences, The George Washington University, 2100 Foxhall Road NW, Washington, DC, 20007, United States.
Abstract:
Microhaplotype loci (microhaps, MHs) are a novel type of molecular marker of less than 300 nucleotides, defined by two or more closely linked SNPs associated in multiple allelic combinations. The value of these markers is enhanced by massively parallel sequencing (MPS), which allows the sequencing of both parental haplotypes at each of the many multiplexed loci. This review describes the features of these multi-SNP markers and documents their value in forensic genetics, focusing on individualization, biogeographic ancestry inference, and mixture deconvolution. Foreseeable applications also include missing person identification, relationship testing, and medical diagnostic applications. The technique is not restricted to humans.
Related Concept Videos
Genetics of Speciation
What is Population Genetics?
What is Genetic Engineering?
Animal Mitochondrial Genetics
Types of Genetic Transfer Between Organisms
Mutation, Gene Flow, and Genetic Drift

