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Updated: Feb 3, 2026

High-throughput Screening for Chemical Modulators of Post-transcriptionally Regulated Genes
Published on: March 3, 2015
High throughput near infrared screening discovers DNA-templated silver clusters with peak fluorescence beyond 950 nm
Steven M Swasey1, Stacy M Copp, Hunter C Nicholson
1Department of Chemistry and Biochemistry, UCSB, Santa Barbara, CA 93106, USA.
Abstract:
We use high throughput near-infrared (NIR) screening technology to discover abundant new DNA-stabilized silver clusters, AgN-DNA, that fluoresce in the NIR. These include the longest wavelength AgN-DNA fluorophores identified to date, with peak emission beyond 950 nm that extends into the NIR II tissue transparency window, and the highest silver content.
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