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Related Concept Videos

Aneurysm I: Introduction01:30

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An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
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Associative learning is a fundamental concept in behavioral psychology, wherein a connection is established between two stimuli or events, leading to a learned response. This process is critical in understanding how behaviors are acquired and modified. Conditioning, the mechanism through which associations are formed, can be divided into two main types: classical conditioning and operant conditioning, each elucidating different aspects of associative learning.
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Vigilant monitoring for aneurysm rupture is essential for patients undergoing aortic surgery.Preoperative Nursing ManagementContinuously monitor the patient for manifestations of aneurysm rupture, such as pallor, weakness, tachycardia, hypotension, abdominal, back, groin, or periumbilical pain, changes in consciousness, and a pulsating abdominal mass. Regularly assess the patient's peripheral pulses.Instruct the patient to consume a clear liquid diet the day before surgery and administer...
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Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
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Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
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Related Experiment Video

Updated: Feb 3, 2026

Minimally Invasive Thumb-sized Pterional Craniotomy for Surgical Clip Ligation of Unruptured Anterior Circulation Aneurysms
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Association Between Unruptured Intracranial Aneurysms and Downstream Stroke.

Monica Lin Chen1, Ajay Gupta1,2, Abhinaba Chatterjee1

  • 1From the Clinical and Translational Neuroscience Unit, Feil Family Brain and Mind Research Institute (M.L.C., A.G., A.C., D.K., G.G., A.E.M., B.B.N., H.K.).

Stroke
|October 26, 2018
PubMed
Summary

This study found no significant link between unruptured intracranial aneurysms and ipsilateral ischemic stroke. Our research indicates aneurysms do not increase the risk of stroke on the same side of the brain.

Keywords:
brain infarctioncerebral infarctionintracranial aneurysmstrokethromboembolism

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Area of Science:

  • Neurology
  • Vascular Neurology
  • Neuroimaging

Background:

  • Case reports suggest unruptured intracranial aneurysms may cause thrombus formation and embolic stroke.
  • Limited data exist to confirm an association between unruptured aneurysms and ischemic stroke.

Purpose of the Study:

  • To investigate the association between unruptured intracranial aneurysms and acute ischemic stroke.
  • To determine if aneurysms ipsilateral to infarcts are more prevalent than contralateral aneurysms.

Main Methods:

  • A within-subjects case-control study of acute ischemic stroke patients.
  • Used magnetic resonance imaging and arterial imaging within 14 days of admission.
  • Compared aneurysm prevalence ipsilateral versus contralateral to anterior circulation infarcts using McNemar test.

Main Results:

  • 176 of 1541 patients (11.4%) had an intracranial aneurysm.
  • Aneurysm prevalence did not differ ipsilateral versus contralateral to infarction (Risk Ratio [RR], 1.2; 95% CI, 0.9-1.5).
  • No significant association found in secondary analyses for single territory, cryptogenic, or cryptogenic single territory strokes.

Conclusions:

  • Contrary to hypothesis, no significant association was found between unruptured intracranial aneurysms and ipsilateral ischemic stroke.
  • Findings suggest unruptured aneurysms may not be a direct cause of ischemic stroke in the anterior circulation.