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Acute Appendicitis Masquerading Distal Intestinal Obstruction Syndrome in Adult Cystic Fibrosis
Sushant M Nanavati1, Hiren Patel2, Gabriel Melki1
1Department of Internal Medicine, St. Joseph's University Medical Center-New York Medical College, USA.
Case Reports in Gastrointestinal Medicine
|October 26, 2018
Summary
Distal Intestinal Obstruction Syndrome (DIOS) is an underdiagnosed gastrointestinal complication in Cystic Fibrosis (CF) patients. This case highlights DIOS as a key differential diagnosis for right lower quadrant abdominal pain in CF, especially in community hospitals.
Area of Science:
- Gastroenterology
- Pulmonology
- Genetics
Background:
- Cystic Fibrosis (CF) commonly impacts the gastrointestinal tract due to secretory and motility issues, often overshadowed by pulmonary symptoms.
- Distal Intestinal Obstruction Syndrome (DIOS) is an infrequent but increasingly recognized gastrointestinal complication in adult CF patients.
Observation:
- A 22-year-old male with CF presented with right lower quadrant abdominal pain, initially suspected as acute appendicitis.
- Diagnostic workup confirmed the patient was experiencing an episode of DIOS.
Findings:
- The case underscores the importance of considering DIOS in the differential diagnosis of right lower quadrant abdominal pain in individuals with CF.
- This is particularly relevant for healthcare providers in community hospitals lacking specialized Cystic Fibrosis care programs.
Implications:
- Increased awareness of DIOS can lead to earlier diagnosis and management in CF patients presenting with abdominal pain.
- This case emphasizes the need for broader recognition of CF-related gastrointestinal complications beyond pulmonary manifestations.
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