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Anabolic Steroid-induced Mania
Daniel G Franey1, Eduardo D Espiridion2
1Psychiatry Clerkship, Frederick Medical Center/West Virginia University, Reading, USA.
Cureus
|October 26, 2018
Summary
Anabolic-androgenic steroid (AAS) use may trigger manic episodes, especially when combined with cannabis. This case highlights the complex psychiatric effects of AAS abuse in real-world scenarios.
Area of Science:
- Psychiatry
- Neuroscience
- Pharmacology
Background:
- Reports suggest psychiatric adverse effects from anabolic-androgenic steroid (AAS) use, but controlled trials lack clarity.
- Real-world AAS abuse often involves confounding synergistic factors complicating clinical assessment.
Observation:
- A patient presented with acute mania, lacking prior psychiatric history or family history.
- Symptoms were resistant to initial pharmacological treatments.
- The patient's mania onset correlated with the initiation of AAS use and was potentially exacerbated by heavy daily cannabis consumption.
Findings:
- The case suggests a link between AAS initiation and acute manic episodes.
- Concurrent heavy cannabis use may potentiate AAS-induced psychiatric symptoms.
- The patient's condition improved with antipsychotic medication and supportive care.
Implications:
- This case underscores the need for careful psychiatric screening in individuals using AAS.
- Understanding synergistic factors like cannabis use is crucial for managing AAS-related psychiatric disturbances.
- Further clinical research is warranted to elucidate the precise mechanisms of AAS-induced psychiatric effects.
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