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In Situ Photoregulation of Carbonic Anhydrase Activity Using Azobenzenesulfonamides

Kanchan Aggarwal1, Mandira Banik1, Brenda Medellin2

  • 1Department of Chemistry , The University of Texas at Austin , 105 East 24th Street, Stop A5300 , Austin , Texas 78712 , United States.

Biochemistry
|October 26, 2018
PubMed
Summary

Researchers developed novel azobenzenesulfonamide probes (CAP1 and CAP2) to control carbonic anhydrase (CA) activity using light. These probes reversibly inhibit or activate the enzyme, offering precise control over biological processes.

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