Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Alterations in Respiration II01:30

Alterations in Respiration II

1.8K
There are numerous types of normal and abnormal respiration. Based on ventilatory movements, breathing patterns are classified as regular, deep, or shallow. Examples include Biot's breathing, Cheyne-Stokes respiration, Kussmaul's breathing, hyperventilation, and hypoventilation. Each pattern is clinically significant and aids in evaluating patients.
In Biot's breathing, the respiratory rate and depth are irregular, alternating between periods of deep gasping and apnea. Common causes...
1.8K
Protein Networks02:26

Protein Networks

4.5K
An organism can have thousands of different proteins, and these proteins must cooperate to ensure the health of an organism. Proteins bind to other proteins and form complexes to carry out their functions. Many proteins interact with multiple other proteins creating a complex network of protein interactions.
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
4.5K
Protein Networks02:26

Protein Networks

2.9K
2.9K
Altered States of Awareness01:06

Altered States of Awareness

1.1K
Altered states of consciousness represent significant deviations from one's normal mental state. These deviations can range from subtle changes in awareness to profound transformations in perception, thought processes, and sensory experiences. Altered states of consciousness can be triggered by various factors, including drug use, meditation, hypnosis, illness, or even intense fatigue.
The ingestion of substances like stimulants or hallucinogens leads to chemical alterations in the brain...
1.1K
Network Covalent Solids02:18

Network Covalent Solids

16.2K
Network covalent solids contain a three-dimensional network of covalently bonded atoms as found in the crystal structures of nonmetals like diamond, graphite, silicon, and some covalent compounds, such as silicon dioxide (sand) and silicon carbide (carborundum, the abrasive on sandpaper). Many minerals have networks of covalent bonds.
To break or to melt a covalent network solid, covalent bonds must be broken. Because covalent bonds are relatively strong, covalent network solids are typically...
16.2K
Alterations in Blood Pressure01:30

Alterations in Blood Pressure

2.2K
Alterations in blood pressure, such as hypertension (high blood pressure) and hypotension (low blood pressure), significantly affect human health. Understanding these conditions' classifications, causes, and symptoms is essential for effective management and treatment.
Hypertension (High blood pressure)
Hypertension occurs when blood pressure readings consistently exceed the normal range. It is diagnosed when systolic blood pressure (the top number, indicating pressure while the heart...
2.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Shared and disease-specific human brain vascular signatures in Alzheimer's disease, frontotemporal dementia, and Huntington's disease.

bioRxiv : the preprint server for biology·2026
Same author

Meningovascular Neuroborreliosis: A Swiss Mini Case Series and Narrative Literature Review.

Case reports in neurology·2026
Same author

Multiplexed optoacoustic tracking and magnetic actuation of labeled blood cells in living mice.

Science advances·2026
Same author

Ratio of Left Atrial and Ventricular Volume as New Marker of Atrial Cardiopathy and Stroke Risk.

Stroke·2026
Same author

Stent Retriever Assisted Endoluminal Reconstruction (STARecon) in Interventional Stroke Management.

Clinical neuroradiology·2026
Same author

Safety of Endovascular Thrombectomy in Isolated Cervical Internal Carotid Artery Occlusion While on Oral Anticoagulation.

Journal of stroke·2026

Related Experiment Video

Updated: Feb 3, 2026

Electroencephalography Network Indices as Biomarkers of Upper Limb Impairment in Chronic Stroke
06:37

Electroencephalography Network Indices as Biomarkers of Upper Limb Impairment in Chronic Stroke

Published on: July 14, 2023

1.3K

Sensorimotor stroke alters hippocampo-thalamic network activity.

Philipp Baumgartner1, Mohamad El Amki1, Oliver Bracko1,2

  • 1Department of Neurology, University Hospital and University of Zurich, Zurich, 8006, Switzerland.

Scientific Reports
|October 27, 2018
PubMed
Summary
This summary is machine-generated.

Stroke survivors

More Related Videos

The Mouse Stroke Unit Protocol with Standardized Neurological Scoring for Translational Mouse Stroke Studies
10:45

The Mouse Stroke Unit Protocol with Standardized Neurological Scoring for Translational Mouse Stroke Studies

Published on: February 7, 2025

1.6K
Soft Pneumatic Robot Modulates Graph Theory Metrics of Brain Network for Hand Rehabilitation After Stroke
05:30

Soft Pneumatic Robot Modulates Graph Theory Metrics of Brain Network for Hand Rehabilitation After Stroke

Published on: October 10, 2025

489

Related Experiment Videos

Last Updated: Feb 3, 2026

Electroencephalography Network Indices as Biomarkers of Upper Limb Impairment in Chronic Stroke
06:37

Electroencephalography Network Indices as Biomarkers of Upper Limb Impairment in Chronic Stroke

Published on: July 14, 2023

1.3K
The Mouse Stroke Unit Protocol with Standardized Neurological Scoring for Translational Mouse Stroke Studies
10:45

The Mouse Stroke Unit Protocol with Standardized Neurological Scoring for Translational Mouse Stroke Studies

Published on: February 7, 2025

1.6K
Soft Pneumatic Robot Modulates Graph Theory Metrics of Brain Network for Hand Rehabilitation After Stroke
05:30

Soft Pneumatic Robot Modulates Graph Theory Metrics of Brain Network for Hand Rehabilitation After Stroke

Published on: October 10, 2025

489

Area of Science:

  • Neuroscience
  • Neurology
  • Medical Imaging

Background:

  • Stroke survivors often face lasting episodic memory problems.
  • Brain areas crucial for memory, like the hippocampus, are often undamaged.
  • This suggests that cognitive deficits stem from disruptions in brain networks distant from the stroke site.

Purpose of the Study:

  • To investigate how ischemic stroke affects hippocampal connections.
  • To understand the role of these network changes in post-stroke memory impairment.

Main Methods:

  • Middle cerebral artery occlusion (MCAA) model in adult rats.
  • Activity-dependent manganese-enhanced MRI (MEMRI) to map neural pathway activity.
  • Behavioral tests and histopathological analysis to assess functional and structural changes.

Main Results:

  • MCAO induced stroke lesions and sensorimotor/cognitive deficits.
  • Memory impairment occurred even without direct hippocampal injury.
  • MEMRI revealed altered Mn2+ distribution, with accumulation in the ipsilateral thalamus in MCAO rats.
  • Histopathology confirmed secondary thalamic degeneration post-stroke.

Conclusions:

  • Remote stroke modifies hippocampal-thalamic network activity.
  • Thalamic structural damage likely contributes to hippocampal-thalamic circuit dysfunction and memory deficits after stroke.