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Summary
A rare granular cell tumor in the orbit caused vision loss in an 18-year-old woman. Surgical removal restored vision, and S-100 protein positivity suggests a Schwann cell origin.
Area of Science:
- Ophthalmology
- Pathology
- Oncology
Background:
- Granular cell tumors (GCTs) are rare neoplasms of uncertain origin.
- Orbital GCTs are exceptionally uncommon, with limited documented cases.
Observation:
- An 18-year-old female presented with proptosis and visual decline over three months.
- An inferior orbital mass was identified as the cause of her symptoms.
Findings:
- Surgical excision of the encapsulated orbital mass successfully restored vision.
- Histopathological analysis confirmed the diagnosis of granular cell tumor.
- Immunohistochemistry revealed S-100 protein positivity, suggesting a potential Schwann cell origin.
Implications:
- This case highlights the unusual presentation of GCTs in the orbit.
- The findings support the hypothesis of Schwann cell differentiation in orbital GCTs.
- Early diagnosis and surgical intervention are crucial for favorable outcomes in orbital masses.