Related Experiment Video
Updated: Feb 3, 2026
10:42
Pretreatment of Lignocellulosic Biomass with Low-cost Ionic Liquids
Published on: August 10, 2016
18.9K
Ionic Liquids for Topical Delivery in Cancer.
Ana Rita Dias1,2, João Costa-Rodrigues1,3,4,5, Cátia Teixeira1,2
1Ciências Químicas e das Biomoléculas, Centro de Investigação em Saúde e Ambiente, Escola Superior de Saúde do Porto, Instituto Politécnico do Porto, Porto, Portugal.
Current Medicinal Chemistry
|October 27, 2018
Summary
Ionic liquids offer unique properties for diverse applications. Recent research highlights their promise in topical drug delivery for skin cancer treatment, advancing medicinal chemistry and pharmaceutical technology.
Area of Science:
- Medicinal Chemistry
- Pharmaceutical Technology
- Materials Science
Background:
- Ionic liquids (ILs) have evolved from "green" solvents (1st generation) to tailored materials (2nd generation).
- A third generation of ILs emerged focusing on clinical applications as drugs or formulation adjuvants.
- Research is increasingly exploring ILs for topical drug delivery, particularly for skin conditions.
Purpose of the Study:
- To highlight the expanding role of ionic liquids in medicinal chemistry.
- To showcase the potential of ionic liquids in pharmaceutical technology for drug delivery.
- To emphasize the growing promise of ionic liquids in treating skin cancers.
Main Methods:
- Literature review on ionic liquid applications.
- Analysis of research trends in ILs for drug delivery.
- Focus on studies related to topical administration and cancer treatment.
Main Results:
- Ionic liquids demonstrate unique properties suitable for advanced applications.
- Third-generation ILs show significant potential for clinical use.
- Topical drug delivery using ILs is a rapidly growing research area with promising outcomes.
Conclusions:
- Ionic liquids are increasingly relevant in medicinal chemistry and pharmaceutical technology.
- ILs offer novel opportunities for drug formulation and delivery systems.
- The application of ILs in topical drug delivery, especially for skin cancers, is a key area for future development.
Related Concept Videos
03:10Ionic Radii
33.5K
Ionic radius is the measure used to describe the size of an ion. A cation always has fewer electrons and the same number of protons as the parent atom; it is smaller than the atom from which it is derived. For example, the covalent radius of an aluminum atom (1s22s22p63s23p1) is 118 pm, whereas the ionic radius of an Al3+ (1s22s22p6) is 68 pm. As electrons are removed from the outer valence shell, the remaining core electrons occupying smaller shells experience a greater effective nuclear...
33.5K
00:42Ionic Bonds
130.8K
Overview
When atoms gain or lose electrons to achieve a more stable electron configuration they form ions. Ionic bonds are electrostatic attractions between ions with opposite charges. Ionic compounds are rigid and brittle when solid and may dissociate into their constituent ions in water. Covalent compounds, by contrast, remain intact unless a chemical reaction breaks them.
Opposing Charges Hold Ions Together in Ionic Compounds
Ionic bonds are reversible electrostatic interactions between ions...
When atoms gain or lose electrons to achieve a more stable electron configuration they form ions. Ionic bonds are electrostatic attractions between ions with opposite charges. Ionic compounds are rigid and brittle when solid and may dissociate into their constituent ions in water. Covalent compounds, by contrast, remain intact unless a chemical reaction breaks them.
Opposing Charges Hold Ions Together in Ionic Compounds
Ionic bonds are reversible electrostatic interactions between ions...
130.8K
02:54Molecular and Ionic Solids
20.1K
Crystalline solids are divided into four types: molecular, ionic, metallic, and covalent network based on the type of constituent units and their interparticle interactions.
Molecular Solids
Molecular crystalline solids, such as ice, sucrose (table sugar), and iodine, are solids that are composed of neutral molecules as their constituent units. These molecules are held together by weak intermolecular forces such as London dispersion forces, dipole-dipole interactions, or hydrogen bonds, which...
Molecular Solids
Molecular crystalline solids, such as ice, sucrose (table sugar), and iodine, are solids that are composed of neutral molecules as their constituent units. These molecules are held together by weak intermolecular forces such as London dispersion forces, dipole-dipole interactions, or hydrogen bonds, which...
20.1K
02:55Solubility of Ionic Compounds
68.2K
Solubility is the measure of the maximum amount of solute that can be dissolved in a given quantity of solvent at a given temperature and pressure. Solubility is usually measured in molarity (M) or moles per liter (mol/L). A compound is termed soluble if it dissolves in water.
68.2K
02:42Ionic Crystal Structures
17.0K
Ionic crystals consist of two or more different kinds of ions that usually have different sizes. The packing of these ions into a crystal structure is more complex than the packing of metal atoms that are the same size.
Most monatomic ions behave as charged spheres, and their attraction for ions of opposite charge is the same in every direction. Consequently, stable structures for ionic compounds result (1) when ions of one charge are surrounded by as many ions as possible of the opposite...
Most monatomic ions behave as charged spheres, and their attraction for ions of opposite charge is the same in every direction. Consequently, stable structures for ionic compounds result (1) when ions of one charge are surrounded by as many ions as possible of the opposite...
17.0K
03:34Ionic Compounds: Formulas and Nomenclature
87.3K
An element composed of atoms that readily lose electrons (a metal) can react with an element composed of atoms that readily gain electrons (a nonmetal) to produce ions through complete electron transfer. The compound formed by this transfer is stabilized by the electrostatic attractions (ionic bonds) between the oppositely charged ions.
87.3K