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Cryptococcal pneumonia: the great mimicker

Lasya Thambidurai1, R Prabhuradhan1, Praveenkumar Singhvi1

  • 1Radiology, Sri Ramachandra Medical College and Hospital, Porur, Chennai, Tamilnadu, India.

BJR Case Reports
|October 27, 2018
PubMed

Insights

Cryptococcal pneumonia, a fungal infection, presents varied radiological findings challenging diagnosis. Image-guided biopsies are essential for confirming this Cryptococcus neoformans infection.

Area of Science:

  • Medical Mycology
  • Infectious Diseases
  • Radiology

Background:

  • Cryptococcal pneumonia is a fungal infection caused by Cryptococcus neoformans.
  • It predominantly affects immunosuppressed individuals but can occur rarely in immunocompetent hosts.

Purpose of the Study:

  • To describe the varied radiological presentations of cryptococcal pneumonia in both immunosuppressed and immunocompetent patients.
  • To highlight the diagnostic challenges posed by the diverse imaging findings.

Main Methods:

  • Case series describing three patients with cryptococcal pneumonia.
  • Review of radiological imaging findings.
  • Discussion of diagnostic difficulties.

Main Results:

  • The study identified varied and challenging radiological presentations of cryptococcal pneumonia.
  • Imaging findings mimicked other pulmonary diseases, complicating diagnosis based on radiology alone.

Conclusions:

  • The diverse imaging manifestations of cryptococcal pneumonia present a significant challenge for radiologists and clinicians.
  • Image-guided biopsies and further investigations are crucial for accurate diagnosis.

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