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Assay Development for High Content Quantification of Sod1 Mutant Protein Aggregate Formation in Living Cells
Published on: October 4, 2017
Development of a novel acaricide, pyflubumide
Takashi Furuya1, Kozo Machiya1, Shinsuke Fujioka1
1Research Center, Research Division, Nihon Nohyaku Co., Ltd., 345 Oyamada-cho, Kawachi-nagano, Osaka 586-0094, Japan.
Abstract:
Pyflubumide is a novel carboxanilide acaricide discovered and developed by Nihon Nohyaku Co., Ltd., that exhibits excellent acaricidal activity against Tetranychus and Panonychus species, including strains that have developed resistance to conventional acaricides. Its safety profile against non-target arthropods is suitable for integrated pest management (IPM) programs. Pyflubumide was registered and launched in Japan in 2015 and Korea in 2017. This paper describes pyflubumide's invention history, synthesis, exploratory synthesis, biological activity, toxicological profile, and mode of action.
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