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Ultrasound-guided Botulinum Toxin-A Injections: A Method of Treating Sialorrhea
Published on: November 9, 2016
Safe Administration of Botulinum Toxin Type A Injections During Pregnancy: A Report of Two Cases
Henriette Krug1, Patricia Krause1, Andreas Kupsch2
1Department of Neurology Charité-University Medicine Berlin Berlin Germany.
Abstract:
Local injections of botulinum toxin type A (BoNT/A) are safe and efficacious to treat focal and segmental dystonia. However, there are no adequate studies in humans regarding the safety of BoNT/A during pregnancy. Despite the fact that 25 case reports have been published on patients who received BoNT/A injections during a total of 31 pregnancies, in only 3 patients were the injections continued beyond the first trimester. We report on 2 females with cervical and segmental dystonia who received BoNT/A injections during pregnancy beyond the first trimester and gave birth to 2 healthy children.
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