Related Experiment Video
Updated: Feb 3, 2026

Catheter-based Endovascular Angioplasty for Fibrosing Mediastinitis-associated Pulmonary Vein Stenosis
Published on: August 26, 2025
The learning curve associated with intracranial angioplasty and stenting: analysis from a single center
Peiquan Zhou1, Guang Zhang1, Zhiyong Ji1
1Department of Neurosurgery, The First Affiliated Hospital of Harbin Medical University, Harbin 150001, China.
Background:
Intracranial angioplasty and stenting is an optional treatment for patients with symptomatic intracranial artery stenosis (IAS) who have failed to respond to standard medical therapy. We aimed to analyze the effect of the operator's learning curve in our center in terms of the safety of intracranial angioplasty and stenting.
Methods:
In this retrospective study, we analyzed patients treated with intracranial angioplasty and stenting in our center between January 2007 and December 2015. The endpoint was peri-procedure complications within 30 days. A risk-adjusted cumulative sum chart was used for the learning curve analysis. Multivariable logistic analysis was also used to evaluate the effect of the learning curve on intracranial angioplasty and stenting.
Results:
A total of 329 patients were included. The overall peri-procedure complication rate was 8.21% (27/329). Multivariate logistic regression analysis showed that operators with experience of >20 cases [odds ratio (OR) =0.229; 95% confidence interval (CI): 0.059-0.893] and >40 cases (OR =0.024; 95% CI: 0.006-0.093) were associated with a low risk of complications compared with operators with experience of ≤20 cases. Furthermore, patients with hypertension (OR =3.595; 95% CI: 1.104-11.702) and stenosis of Mori classification C (OR =28.562; 95% CI: 4.788-170.395) were associated with a high risk of complications. The observed outcome was better than expected (more negative deflections) after the 30th consecutive case.
Conclusions:
The level of operator experience can influence the risk of peri-procedure complications associated with intracranial angioplasty and stenting. A total of 30 consecutive cases is required for an operator to overcome the learning curve.
More Related Videos
11:00Experimental Investigation of Secondary Flow Structures Downstream of a Model Type IV Stent Failure in a 180° Curved Artery Test Section
Published on: July 19, 2016
12:30Vascular Gene Transfer from Metallic Stent Surfaces Using Adenoviral Vectors Tethered through Hydrolysable Cross-linkers
Published on: August 12, 2014
Related Concept Videos
Precipitation Titration Curve: Analysis
Bending of Curved Members - Strain Analysis
The important part of bending analysis for such a member...
Sieve Analysis and Grading Curves
Lattice Centering and Coordination Number
Types of Unit Cells
Imagine taking a large number of identical...
Center of Gravity
Center of Gravity
To determine its location, the principle of moments can be utilized by dividing the object into...