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Updated: Feb 3, 2026

Assessment and Communication for People with Disorders of Consciousness
Published on: August 1, 2017
[Causes of stroke among young people: role of the internist]
Abire Allaoui1, Khadija Echchilali1, Mina Moudatir1
1Service de Médecine Interne, CHU Ibn Rochd, Casablanca, Faculté de Médecine Privée Casablanca, Université Hassan II, Maroc.
Insights
Brain ischemia in young adults has diverse causes, often linked to autoimmune diseases like systemic lupus erythematosus and antiphospholipid syndrome. Early diagnosis and treatment by internists are crucial for managing this condition.
Area of Science:
- Neurology
- Internal Medicine
- Rheumatology
Background:
- Brain ischemia in young individuals presents unique etiological and prognostic challenges.
- Internal medicine plays a key role in diagnosing and managing these cases, often involving complex patient histories.
Purpose of the Study:
- To investigate the specific causes of brain ischemia in young patients treated at a Department of Internal Medicine.
- To provide insights into the diverse etiologies and clinical characteristics of ischemic strokes in a young population.
Main Methods:
- A retrospective study analyzing medical records of young patients hospitalized between 2000 and 2014.
- Utilized CT scan angiography and/or MRI angiography to determine stroke nature and location.
- Clinical examination and targeted investigations identified underlying causes.
Main Results:
- Twenty-five young patients (average age 36±7) were included. Key risk factors included smoking (32%), diabetes (8%), and hypertension (8%).
- Common causes identified were acute systemic lupus (32%) often with antiphospholipid syndrome (80%), Behcet's disease (16%), and Takayasu's disease (12%).
- Treatment involved anti-aggregation therapy, corticosteroids, and immunosuppressants in 76% of cases.
Conclusions:
- Brain ischemia in young people stems from multiple, often autoimmune-related, causes.
- Internists are vital in identifying these specific etiologies.
- Further research is needed to understand recurrence risks and optimize therapeutic strategies.
Abstract:
In young people brain ischemias vary according to their cause and prognosis. In internal medicine they have a specific cause, considering the tertiary source of recruitment. Our study aimed to provide informations about some specific causes of this disease in young subject. We conducted a retrospective study by reviewing the medical records of young patients hospitalized at the Department of Internal Medicine in Casablanca over the period 2000-2014. All patients underwent CT scan angiography and/or magnetic resonance angiography that determined the nature and the topography of the ischemic stroke. Clinical examination was followed by appropriate investigations to determine the cause of brain ischemia. Data were collected from twenty-five patients, with a sex ratio of 0.73 and an average age of 36±7. Smoking was reported in 32% of cases, diabetes and high blood pressure were found in 8% of cases. Amnesia and migraine episodes were found in 24% of cases. Combination estrogen-progestin and a history of miscarriage were reportedin 12% of cases. Ischemic strokes were mainly caused by acute systemic lupus (32%) associated with antiphospholipid syndrome (80%), Behcet's disease (16%), Takayasu's disease (12%). In addition to anti-aggregation treatment, 76% of patients underwent corticosteroid and immunosuppressive therapies. Internists are involved in the treatment of patients with ischemic stroke, in particular to determine its cause. The causes of brain ischemias in young people are multiple. Research has to be rigorous in order to identify specific causes, to evaluate the risk of recidivism and to establish a therapeutic approach.
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