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Precipitating factors of decompensation of heart failure related to treatment adherence: multicenter study-EMBRACE

Eneida Rejane Rabelo-Silva1,2, Marco Aurélio Lumertz Saffi2, Graziella Badin Aliti1,2

  • 1Universidade Federal do Rio Grande do Sul (UFRGS). Escola de Enfermagem. Porto Alegre, Rio Grande do Sul, Brasil.

Revista Gaucha De Enfermagem
|October 27, 2018
PubMed

Insights

Poor adherence to heart failure treatment is the primary cause of decompensation. Patients with irregular medication use face a significantly higher risk of hospitalization due to non-adherence.

Area of Science:

  • Cardiology
  • Internal Medicine
  • Clinical Research

Background:

  • Heart failure decompensation leads to frequent hospitalizations.
  • Patient adherence to treatment is crucial for managing heart failure.
  • Understanding precipitating factors of decompensation is vital for improving patient outcomes.

Purpose of the Study:

  • To identify and compare the factors leading to heart failure decompensation in patients with varying levels of treatment adherence.
  • To investigate the specific impact of non-adherence on the risk of heart failure exacerbation.

Main Methods:

  • A multicenter, cross-sectional cohort study was conducted.
  • 556 adult patients with decompensated heart failure (functional class III/IV) were enrolled.
  • Data on precipitating factors, including medication use and lifestyle, were collected via structured questionnaires.

Main Results:

  • Poor adherence was identified as the primary factor for decompensation, accounting for 55% of cases.
  • Patients reporting irregular medication use in the preceding week had a 22% increased risk of hospitalization due to non-adherence.
  • Inadequate salt and fluid intake were also noted as contributing factors to poor adherence.

Conclusions:

  • Poor adherence to treatment is the leading cause of heart failure exacerbation.
  • Interventions aimed at improving medication adherence are critical for reducing heart failure hospitalizations.
Abstract

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